About   Help   FAQ
Vti1a Gene Detail
Summary
  • Symbol
    Vti1a
  • Name
    vesicle transport through interaction with t-SNAREs 1A
  • Synonyms
    1110014F16Rik, 1110018K19Rik, 4921537J05Rik, Vti1-rp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1855699
    NCBI Gene: 53611
  • Gene Overview
    MyGene.info: VTI1A
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:55316295-55627309 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 51.35 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2430 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1855699
protein coding gene Chr19:55316057-55627461 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025259
protein coding gene Chr19:55584335-55913949 (+)
A/J MGP_AJ_G0025235
protein coding gene Chr19:52856651-53166151 (+)
AKR/J MGP_AKRJ_G0025204
protein coding gene Chr19:54524767-54839750 (+)
BALB/cJ MGP_BALBcJ_G0025230
protein coding gene Chr19:52927149-53247269 (+)
C3H/HeJ MGP_C3HHeJ_G0024990
protein coding gene Chr19:54749315-55068976 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025673
protein coding gene Chr19:56954893-57279087 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023085
protein coding gene Chr19:51784911-52094562 (+)
CAST/EiJ MGP_CASTEiJ_G0024455
protein coding gene Chr19:54741769-55071798 (+)
CBA/J MGP_CBAJ_G0024970
protein coding gene Chr19:59755534-60091049 (+)
DBA/2J MGP_DBA2J_G0025102
protein coding gene Chr19:52651185-52962680 (+)
FVB/NJ MGP_FVBNJ_G0025063
protein coding gene Chr19:52354580-52665136 (+)
LP/J MGP_LPJ_G0025188
protein coding gene Chr19:55459388-55778735 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025096
protein coding gene Chr19:59120061-59468435 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025731
protein coding gene Chr19:54735991-55055132 (+)
PWK/PhJ MGP_PWKPhJ_G0024203
protein coding gene Chr19:52583103-52896060 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024006
protein coding gene Chr19:53402433-53715155 (+)
WSB/EiJ MGP_WSBEiJ_G0024525
protein coding gene Chr19:54853425-55178002 (+)



Homology
more
  • Human Ortholog
    VTI1A, vesicle transport through interaction with t-SNAREs 1A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    VTI1A, vesicle transport through interaction with t-SNAREs 1A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MMDS3, MVti1, Vti1-rp2, VTI1RP2
  • Links
    NCBI Gene ID: 143187
    neXtProt AC: NX_Q96AJ9
    UniProt: Q96AJ9

  • Chr Location
    10q25.2; chr10:112446988-112947204 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    28 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024983 Ensembl Gene Model | MGI Sequence Detail 311015 C57BL/6J ±  kb
    transcript ENSMUST00000223690 Ensembl | MGI Sequence Detail 4175 Not Applicable  
    polypeptide ENSMUSP00000153629 Ensembl | MGI Sequence Detail 224 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 21
      Primer pair 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1915752, MGI:1915845, MGI:1918188
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 11
    • Earliest
      J:45672 Lupashin VV, et al., Characterization of a novel yeast SNARE protein implicated in Golgi retrograde traffic. Mol Biol Cell. 1997 Dec;8(12):2659-76
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory