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Vti1a
Gene Detail
Symbol

Name
ID
Vti1a
vesicle transport through interaction with t-SNAREs 1A
MGI:1855699
Synonyms
1110014F16Rik, 1110018K19Rik, 4921537J05Rik, Vti1-rp2
Feature Type
protein coding gene
Genetic Map
Chromosome 19
51.35 cM, cytoband D2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:55316351-55626561 bp, + strand
From Ensembl annotation of GRCm38

  310211 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:39963  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Vti1a

Human
homologs
Human Homolog VTI1A, vesicle transport through interaction with t-SNAREs 1A
NCBI Gene ID 143187
neXtProt AC  NX_Q96AJ9
Human Synonyms  MMDS3, MVti1, Vti1-rp2, VTI1RP2
Human Chr (Location)  10q25.2; chr10:112446998-112855364 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(67) : Gene trapped(64) Targeted(3)
Incidental mutations (data from Mutagenetix )
 
Mice homozygous for a knock-out allele are viable and fertile.
 
Interactions
Vti1a interacts with 296 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(7)
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024983 Ensembl Gene Model | MGI Sequence Detail 310211 C57BL/6J ±  kb
transcript ENSMUST00000095950 Ensembl | MGI Sequence Detail 3405 Not Applicable 
polypeptide ENSMUSP00000093644 Ensembl | MGI Sequence Detail 217 Not Applicable 

For the selected sequences
All sequences(92) RefSeq(32) UniProt(7)
Polymorphisms
SNPs within 2kb(2448 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000727 Target SNARE coiled-coil domain
InterPro IPR010989 t-SNARE
InterPro IPR007705 Vesicle transport v-SNARE, N-terminal
Protein Ontology PR:000017358 vesicle transport through interaction with t-SNAREs homolog 1A
References
(Earliest) J:45672 Lupashin VV, et al., Characterization of a novel yeast SNARE protein implicated in Golgi retrograde traffic. Mol Biol Cell. 1997 Dec;8(12):2659-76
(Latest) J:213492 Walter AM, et al., The SNARE protein vti1a functions in dense-core vesicle biogenesis. EMBO J. 2014 Aug 1;33(15):1681-97
All references(42)
Other
accession IDs
MGI:1915752, MGI:1915845, MGI:1918188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory