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Tmod2
Gene Detail
Symbol

Name
ID
Tmod2
tropomodulin 2
MGI:1355335
Synonyms
neural tropomodulin, N-Tmod, NTMOD
Feature Type
protein coding gene
Genetic Map
Chromosome 9
42.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:75565621-75611325 bp, - strand
From Ensembl annotation of GRCm38

  45705 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: tropomodulin
Gene Tree: Tmod2
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in enhanced LTP, hyperactivity, impaired startle response, and impaired learning.
 
Interactions
Tmod2 interacts with 560 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process actin filament organization, learning or memory, ...
Component cytoplasm, cytoskeleton, ...
Function actin binding, tropomyosin binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (6)    Tissues (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 2
Northern blot 4
cDNA source data(11)
External Resources: Allen Institute   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(15) Primer pair(1) Other(1)
Microarray probesets(8)
Other database
links
Ensembl Gene ModelENSMUSG00000032186 (Evidence)
Entrez Gene50876, 102636997
DFCITC1598593, TC1589078, TC1575076, TC1676995, TC1720615
DoTSDT.55126270, DT.40134046, DT.110638895, DT.101380432, DT.99854075, DT.94190247, DT.91337113, DT.55236191
NIA Mouse Gene IndexU031100
Consensus CDS ProjectCCDS23345.1
International Mouse Knockout Project StatusTmod2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032186 Ensembl Gene Model | MGI Sequence Detail 45705 C57BL/6J ±  kb
transcript ENSMUST00000064433 Ensembl | MGI Sequence Detail 9893 Not Applicable 
polypeptide ENSMUSP00000069956 Ensembl | MGI Sequence Detail 351 Not Applicable 

For the selected sequences
All sequences(41) UniProt(1)
Polymorphisms
SNPs within 2kb(428 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004934 Tropomodulin
Protein Ontology PR:000016445 tropomodulin-2
References
(Earliest) J:60558 Cox PR, et al., Sequencing, expression analysis, and mapping of three unique human tropomodulin genes and their mouse orthologs. Genomics. 2000 Jan 1;63(1):97-107
(Latest) J:208725 Sui Z, et al., Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver. Blood. 2014 Jan 30;123(5):758-67
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory