Nasp
Gene Detail

Symbol Name ID

Nasp nuclear autoantigenic sperm protein (histone-binding) MGI:1355328

Synonyms

5033430J04Rik, D4Ertd767e, Epcs32, Nasp-T

Feature Type

protein coding gene

Genetic Map

Chromosome 4

53.24 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr4:116601052-116627941 bp, - strand From VEGA annotation of GRCm38   26890 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:1856  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Nasp

Human homologs

Human Homolog		NASP, nuclear autoantigenic sperm protein (histone-binding)
NCBI Gene ID		4678
neXtProt AC		NX_P49321
Human Synonyms		FLB7527, PRO1999
Human Chr (Location)		1p34.1; chr1:46049660-46084578 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(93) : Targeted(2) Gene trapped(91)
 

Mice homozygous for a null mutation display embryonic lethality before implantation.

 

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	blastocyst development, cell cycle, ...
Component	cytoplasm, nucleus
Function	histone binding, Hsp90 protein binding, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (44)    Tissues (11)    Images (19)
Theiler Stages: 11, 23, 28

Assay Type	Results
RNA in situ	44

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(18) Genomic(1) cDNA(16) Primer pair(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000009439 (Evidence)
Ensembl Gene Model	ENSMUSG00000028693 (Evidence)
Entrez Gene	50927 (Evidence)
DFCI	TC1572253, TC1578404, TC1592680, TC1609654
DoTS	DT.101390883, DT.102536048, DT.103577505, DT.94200275, DT.94274398, DT.99861696
NIA Mouse Gene Index	U025415
Consensus CDS Project	CCDS18513.1, CCDS38852.1
International Mouse Knockout Project Status	Nasp

Sequences

Length	Strain/Species
genomic	OTTMUSG00000009439	VEGA Gene Model | MGI Sequence Detail	26890	C57BL/6J
transcript	OTTMUST00000021500	VEGA | MGI Sequence Detail	2520	Not Applicable
polypeptide	OTTMUSP00000009823	VEGA | MGI Sequence Detail	773	Not Applicable

All sequences(62) RefSeq(4) UniProt(4)

Polymorphisms

SNPs(70 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011990	Tetratricopeptide-like helical
InterPro	IPR019734	Tetratricopeptide repeat
InterPro	IPR013026	Tetratricopeptide repeat-containing domain
InterPro	IPR019544	Tetratricopeptide, SHNi-TPR domain
InterPro	IPR001440	Tetratricopeptide TPR-1
Protein Ontology	PR:000010993	nuclear autoantigenic sperm protein

References

(Earliest) J:54434 Leimeister C, et al., Screen for genes regulated during early kidney morphogenesis. Dev Genet. 1999;24(3-4):273-83
(Latest) J:179807 Grellscheid S, et al., Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2beta in development. PLoS Genet. 2011 Dec;7(12):e1002390
All references(50)

Other accession IDs

MGI:1289187, MGI:1914654, MGI:2140195, MGI:2145613