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Il27ra
Gene Detail
Symbol

Name
ID
Il27ra
interleukin 27 receptor, alpha
MGI:1355318
Synonyms
IL-27R, Tccr, WSX-1
Feature Type
protein coding gene
Genetic Map
Chromosome 8
40.26 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:84030287-84042575 bp, - strand
From Ensembl annotation of GRCm38

  12289 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3562  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: IL27RA
Gene Tree: Il27ra

Human
homologs
IL27RA, interleukin 27 receptor, alpha
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9466
neXtProt AC: NX_Q6UWB1

Human Synonyms: CRL1, IL27R, IL-27RA, TCCR, WSX1, zcytor1

Human Chr (Location): 19p13.11; chr19:14031740-14052919 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
T helper 1 response and responses to parasitic and bacterial infection are altered in homozygous mutant mice.
 
Interactions
Il27ra interacts with 113 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (16)    Tissues (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 16
cDNA source data(17)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(17) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000005465 (Evidence)
Entrez Gene 50931 (Evidence)
UniGene 38386
DFCI TC1584309, TC1739831
DoTS DT.527056, DT.94176828
NIA Mouse Gene Index U030021
Consensus CDS Project CCDS22465.1
International Mouse Phenotyping Consortium Status Il27ra
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000005465 Ensembl Gene Model | MGI Sequence Detail 12289 C57BL/6J ±  kb
transcript ENSMUST00000005601 Ensembl | MGI Sequence Detail 2657 Not Applicable 
polypeptide ENSMUSP00000005601 Ensembl | MGI Sequence Detail 623 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(125 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
Protein Ontology PR:000009002 interleukin-27 receptor subunit alpha
References
(Earliest) J:47617 Sprecher CA, et al., Cloning and characterization of a novel class I cytokine receptor. Biochem Biophys Res Commun. 1998 May 8;246(1):82-90
(Latest) J:219798 Zhu C, et al., An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nat Commun. 2015;6:6072
All references(91)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory