About   Help   FAQ
C1ra Gene Detail
Summary
  • Symbol
    C1ra
  • Name
    complement component 1, r subcomponent A
  • Synonyms
    mC1rA
  • Feature Type
    protein coding gene
  • IDs
    MGI:1355313
    NCBI Gene: 50909
  • Gene Overview
    MyGene.info: C1R
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124512621-124523440 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.16 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    56 from dbSNP Build 142
  • Strain Annotations
    10
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1355313
protein coding gene Chr6:124512405-124523443 (.)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0031156
protein coding gene Chr6:126359543-126370480 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0030916
protein coding gene Chr6:136259060-136272583 (+)
DBA/2J MGP_DBA2J_G0031072
protein coding gene Chr6:121844580-121862463 (+)
FVB/NJ MGP_FVBNJ_G0031022
protein coding gene Chr6:120780727-120890643 (+)
LP/J MGP_LPJ_G0031153
protein coding gene Chr6:127979242-127996737 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031060
protein coding gene Chr6:140223665-140248625 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031723
protein coding gene Chr6:126207838-126224205 (+)
PWK/PhJ MGP_PWKPhJ_G0030054
protein coding gene Chr6:120096938-120101492 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029883
protein coding gene Chr6:124328839-124361680 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    C1R, complement C1r
  • Vertebrate Orthologs
    9
  • Human Ortholog
    C1R, complement C1r
    Orthology source: HGNC, HomoloGene
  • Synonyms
    EDSPD1
  • Links
    NCBI Gene ID: 715
    neXtProt AC: NX_P00736
    UniProt: P00736

  • Chr Location
    12p13.31; chr12:7080209-7092447 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 50909 NCBI Gene Model | MGI Sequence Detail 10820 C57BL/6J ±  kb
transcript NM_023143 RefSeq | MGI Sequence Detail 2762 C57BL/6  
polypeptide Q8CG16 UniProt | EBI | MGI Sequence Detail 707 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2141380, MGI:3719032
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:61131 Lawson PR, et al., A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes. Int Immunol. 2000 Mar;12(3):231-40
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory