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C1ra Gene Detail
Summary
  • Symbol
    C1ra
  • Name
    complement component 1, r subcomponent A
  • Synonyms
    mC1rA
  • Feature Type
    protein coding gene
  • IDs
    MGI:1355313
    NCBI Gene: 50909
Location & Maps
more
  • Sequence Map
    Chr6:124512621-124523440 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10820 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    C1R, complement component 1, r subcomponent
  • Vertebrate Orthologs
    9
  • Human Ortholog
    C1R, complement component 1, r subcomponent
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 715
    neXtProt AC: NX_P00736

  • Chr Location
    12p13

Human Diseases
more
  • Diseases
    1 with human C1R associations

Human Disease Mouse Models
       Complement Component C1r/C1s Deficiency   OMIM: 216950
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 50909 NCBI Gene Model | MGI Sequence Detail 10820 C57BL/6J ±  kb
transcript NM_023143 RefSeq | MGI Sequence Detail 2762 C57BL/6  
polypeptide Q8CG16 UniProt | EBI | MGI Sequence Detail 707 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    90 from dbSNP Build 137
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2141380, MGI:3719032
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:61131 Lawson PR, et al., A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes. Int Immunol. 2000 Mar;12(3):231-40
  • Latest
    J:174459 Boyle MP, et al., Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. J Comp Neurol. 2011 Aug 1;519(11):2061-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory