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C1s1 Gene Detail
Summary
  • Symbol
    C1s1
  • Name
    complement component 1, s subcomponent 1
  • Synonyms
    C1s
  • Feature Type
    protein coding gene
  • IDs
    MGI:1355312
    NCBI Gene: 50908
  • Gene Overview
    MyGene.info: C1S
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124530345-124542359 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    198 from dbSNP Build 142
  • Strain Annotations
    9
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1355312
protein coding gene Chr6:124530344-124542392 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0031234
protein coding gene Chr6:122562325-122582803 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0031692
protein coding gene Chr6:131139417-131295963 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030340
protein coding gene Chr6:126680920-126694248 (-)
CBA/J MGP_CBAJ_G0030918
protein coding gene Chr6:136321946-136337039 (-)
DBA/2J MGP_DBA2J_G0031074
protein coding gene Chr6:122028159-122049303 (-)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0031725
protein coding gene Chr6:126355727-126370167 (-)
PWK/PhJ MGP_PWKPhJ_G0030055
protein coding gene Chr6:120182491-120187763 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0030423
protein coding gene Chr6:126694478-126729742 (-)



Homology
more
  • Human Ortholog
    C1S, complement C1s
  • Vertebrate Orthologs
    10
  • Human Ortholog
    C1S, complement C1s
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EDSPD2
  • Links
    NCBI Gene ID: 716
    neXtProt AC: NX_P09871
    UniProt: P09871

  • Chr Location
    12p13.31; chr12:7060676-7071032 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038521 Ensembl Gene Model | MGI Sequence Detail 12015 C57BL/6J ±  kb
transcript ENSMUST00000160505 Ensembl | MGI Sequence Detail 2946 Not Applicable  
polypeptide ENSMUSP00000125531 Ensembl | MGI Sequence Detail 694 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 82
    cDNA 80
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1353567, MGI:2141372, MGI:2141399
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 6
  • Earliest
    J:61131 Lawson PR, et al., A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes. Int Immunol. 2000 Mar;12(3):231-40
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory