About   Help   FAQ
C1s1 Gene Detail
Summary
  • Symbol
    C1s1
  • Name
    complement component 1, s subcomponent 1
  • Synonyms
    C1s
  • Feature Type
    protein coding gene
  • IDs
    MGI:1355312
    NCBI Gene: 50908
Location & Maps
more
  • Sequence Map
    Chr6:124530345-124542359 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12015 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    C1S, complement component 1, s subcomponent
  • Vertebrate Orthologs
    10
  • Human Ortholog
    C1S, complement component 1, s subcomponent
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 716
    neXtProt AC: NX_P09871

  • Chr Location
    12p13; chr12:7060676-7071032 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human C1S associations

Human Disease Mouse Models
       Complement Component C1s Deficiency; C1SD   OMIM: 613783
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034941 VEGA Gene Model | MGI Sequence Detail 12015 C57BL/6J ±  kb
transcript OTTMUST00000088914 VEGA | MGI Sequence Detail 2906 Not Applicable  
polypeptide OTTMUSP00000048526 VEGA | MGI Sequence Detail 694 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    310 from dbSNP Build 137
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 79
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1353567, MGI:2141372, MGI:2141399
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 5
  • Earliest
    J:61131 Lawson PR, et al., A novel PCR-based technique using expressed sequence tags and gene homology for murine genetic mapping: localization of the complement genes. Int Immunol. 2000 Mar;12(3):231-40
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory