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Hs6st3 Gene Detail
Summary
  • Symbol
    Hs6st3
  • Name
    heparan sulfate 6-O-sulfotransferase 3
  • Synonyms
    6OST3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354960
    NCBI Gene: 50787
Location & Maps
more
  • Sequence Map
    Chr14:119138415-119869594 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      731180 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 62.67 cM, cytoband E4
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HS6ST3, heparan sulfate 6-O-sulfotransferase 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HS6ST3, heparan sulfate 6-O-sulfotransferase 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HS6ST-3
  • Links
    NCBI Gene ID: 266722
    neXtProt AC: NX_Q8IZP7

  • Chr Location
    13q32.1; chr13:96090536-96839562 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Hs6st3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053465 Ensembl Gene Model | MGI Sequence Detail 731180 C57BL/6J ±  kb
transcript ENSMUST00000065904 Ensembl | MGI Sequence Detail 1413 Not Applicable  
polypeptide ENSMUSP00000070394 Ensembl | MGI Sequence Detail 470 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    3509 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 7
    Primer pair 4

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:60682 Habuchi H, et al., The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine. J Biol Chem. 2000 Jan 28;275(4):2859-68
  • Latest
    J:195563 Anower-E-Khuda MF, et al., Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin. J Biol Chem. 2013 Feb 8;288(6):3705-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory