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Nrbf2 Gene Detail
Summary
  • Symbol
    Nrbf2
  • Name
    nuclear receptor binding factor 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354950
    NCBI Gene: 641340
  • Gene Overview
    MyGene.info: NRBF2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:67266689-67285305 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 34.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    178 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354950
protein coding gene Chr10:67266689-67285345 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017323
protein coding gene Chr10:67013669-67034181 (-)
A/J MGP_AJ_G0017300
protein coding gene Chr10:64778991-64797469 (-)
AKR/J MGP_AKRJ_G0017261
protein coding gene Chr10:66561748-66580374 (-)
BALB/cJ MGP_BALBcJ_G0017260
protein coding gene Chr10:64984980-65003640 (-)
C3H/HeJ MGP_C3HHeJ_G0017084
protein coding gene Chr10:66526248-66544823 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017718
protein coding gene Chr10:69448299-69467139 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015408
protein coding gene Chr10:61464090-61483705 (-)
CAST/EiJ MGP_CASTEiJ_G0016654
protein coding gene Chr10:66570898-66591278 (-)
CBA/J MGP_CBAJ_G0017056
protein coding gene Chr10:72087697-72106282 (-)
DBA/2J MGP_DBA2J_G0017161
protein coding gene Chr10:64159833-64178710 (-)
FVB/NJ MGP_FVBNJ_G0017154
protein coding gene Chr10:63331184-63349960 (-)
LP/J MGP_LPJ_G0017234
protein coding gene Chr10:67419842-67438358 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017182
protein coding gene Chr10:74336076-74355599 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017757
protein coding gene Chr10:66442146-66461788 (-)
PWK/PhJ MGP_PWKPhJ_G0016438
protein coding gene Chr10:63947995-63966908 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016220
protein coding gene Chr10:65779939-65821116 (-)
WSB/EiJ MGP_WSBEiJ_G0016718
protein coding gene Chr10:66369941-66388843 (-)



Homology
more
  • Human Ortholog
    NRBF2, nuclear receptor binding factor 2
  • Vertebrate Orthologs
    12
  • Human Ortholog
    NRBF2, nuclear receptor binding factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    COPR, COPR1, COPR2, NRBF-2
  • Links
    NCBI Gene ID: 29982
    neXtProt AC: NX_Q96F24
    UniProt: Q96F24

  • Chr Location
    10q21.3; chr10:63133247-63155031 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41473
    1 human;1 mouse;3 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NRBF2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075000 Ensembl Gene Model | MGI Sequence Detail 18617 C57BL/6J ±  kb
transcript ENSMUST00000077839 Ensembl | MGI Sequence Detail 1813 Not Applicable  
polypeptide ENSMUSP00000097254 Ensembl | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 5
References
more
  • Summaries
    All 31
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:220500 Lu J, et al., NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity. Nat Commun. 2014;5:3920

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory