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Klf13
Gene Detail
 Symbol
Name
ID
Klf13
Kruppel-like factor 13
MGI:1354948
Synonyms 9430029L20Rik, Bteb3, FKLF-2, Klf13, NSLP1, RFLAT1, RFLAT-1
Feature Type protein coding gene
Genetic Map
Chromosome 7
34.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:63886350-63887675 bp
From MGI annotation of GRCm38

  1326 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32288  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Klf13

Human
homologs
Human Homolog KLF13, Kruppel-like factor 13
NCBI Gene ID 51621
neXtProt AC  NX_Q9Y2Y9
Human Synonyms  BTEB3, FKLF2, NSLP1, RFLAT1, RFLAT-1
Human Chr (Location)  15q12; chr15:31326880-31377899 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a disruption in this gene are grossly normal. Prolonged thymocyte survival leads to an enlarged thymus and spleen. Mice homozygous for a different allele exhibit splenomegaly and abnormal erythropoiesis.
 
Interactions
Klf13 interacts with 449 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process negative regulation of cell proliferation, negative regulation of erythrocyte differentiation, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (199)    Tissues (171)    Images (40)
Theiler Stages: 2, 3, 4, 5, 12, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 26, 27, 28
Assay TypeResults
Immunohistochemistry 26
RNA in situ 152
Northern blot 9
RT-PCR 12
cDNA source data(105)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(112) cDNA(108) Primer pair(3) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000044885 (Evidence)
Ensembl Gene ModelENSMUSG00000052040 (Evidence)
Entrez Gene50794 (Evidence)
UniGene240473
DFCITC1577792, TC1598996
DoTSDT.491694, DT.533430, DT.91342629, DT.99871828
NIA Mouse Gene IndexU028669, U319683
Consensus CDS ProjectCCDS21331.1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044885 VEGA Gene Model | MGI Sequence Detail 52569 C57BL/6J ±  kb
transcript OTTMUST00000117941 VEGA | MGI Sequence Detail 6400 Not Applicable 
polypeptide OTTMUSP00000065878 VEGA | MGI Sequence Detail 289 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(428 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000009357 krueppel-like factor 13
References (Earliest) J:60553 Martin KM, et al., Mouse BTEB3, a new member of the basic transcription element binding protein (BTEB) family, activates expression from GC-rich minimal promoter regions. Biochem J. 2000 Feb 1;345 Pt 3:529-33
(Latest) J:192467 Heard ME, et al., The reproductive phenotype of mice null for transcription factor Kruppel-like factor 13 suggests compensatory function of family member Kruppel-like factor 9 in the peri-implantation uterus. Biol Reprod. 2012 Nov;87(5):115
All references(49)
Other
accession IDs
MGI:1915649, MGI:1924575

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory