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Plpp2 Gene Detail
Summary
  • Symbol
    Plpp2
  • Name
    phospholipid phosphatase 2
  • Synonyms
    Lpp2, Ppap2c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354945
    NCBI Gene: 50784
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79526424-79533787 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354945
protein coding gene Chr10:79526424-79533796 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017444
protein coding gene Chr10:80056407-80063749 (-)
A/J MGP_AJ_G0017422
protein coding gene Chr10:77276282-77283624 (-)
AKR/J MGP_AKRJ_G0017383
protein coding gene Chr10:79369277-79376619 (-)
BALB/cJ MGP_BALBcJ_G0017384
protein coding gene Chr10:77502726-77509918 (-)
C3H/HeJ MGP_C3HHeJ_G0017207
protein coding gene Chr10:79483151-79490562 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017838
protein coding gene Chr10:82825259-82832601 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015526
protein coding gene Chr10:73502797-73510479 (-)
CAST/EiJ MGP_CASTEiJ_G0016774
protein coding gene Chr10:79658549-79665883 (-)
CBA/J MGP_CBAJ_G0017179
protein coding gene Chr10:86048206-86055548 (-)
DBA/2J MGP_DBA2J_G0017285
protein coding gene Chr10:76493331-76500673 (-)
FVB/NJ MGP_FVBNJ_G0017279
protein coding gene Chr10:75649791-75657849 (-)
LP/J MGP_LPJ_G0017356
protein coding gene Chr10:80532058-80539400 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017305
protein coding gene Chr10:88035234-88042708 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017879
protein coding gene Chr10:79349102-79356445 (-)
PWK/PhJ MGP_PWKPhJ_G0016555
protein coding gene Chr10:76349289-76356708 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016344
protein coding gene Chr10:78340464-78347745 (-)
WSB/EiJ MGP_WSBEiJ_G0016834
protein coding gene Chr10:79382891-79390236 (-)



Homology
more
  • Human Ortholog
    PLPP2, phospholipid phosphatase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PLPP2, phospholipid phosphatase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LPP2, PAP-2c, PAP2-g, PPAP2C
  • Links
    NCBI Gene ID: 8612
    neXtProt AC: NX_O43688
    UniProt: O43688

  • Chr Location
    19p13.3; chr19:281040-291435 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 50784 NCBI Gene Model | MGI Sequence Detail 7364 C57BL/6J ±  kb
transcript NM_015817 RefSeq | MGI Sequence Detail 1651 C57BL/6  
polypeptide Q9DAX2 UniProt | EBI | MGI Sequence Detail 276 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 148
    Genomic 1
    cDNA 146
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory