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Fbxo44 Gene Detail
Summary
  • Symbol
    Fbxo44
  • Name
    F-box protein 44
  • Synonyms
    FBG3, FBX30, Fbx6a, Fbxo6a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354744
    NCBI Gene: 230903
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:148237256-148244663 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 78.67 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354744
 protein coding gene Chr4:148237256-148244939 (-)
129S1/SvImJ ENSMUSG00200045528
 protein coding gene Chr4:139273357-139281033 (-)
A/J ENSMUSG00195030180
 protein coding gene Chr4:140931011-140938693 (-)
AKR/J ENSMUSG00220046601
 protein coding gene Chr4:140511674-140519353 (-)
BALB/cJ ENSMUSG00180042404
 protein coding gene Chr4:138613675-138621359 (-)
C3H/HeJ ENSMUSG00175036414
 protein coding gene Chr4:141892183-141899862 (-)
C57BL/6NJ ENSMUSG00215047075
 protein coding gene Chr4:140737310-140744992 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026796
 protein coding gene Chr4:137995564-138002965 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210026008
 protein coding gene Chr4:140543869-140551547 (-)
DBA/2J ENSMUSG00185016499
 protein coding gene Chr4:144102014-144109695 (-)
FVB/NJ ENSMUSG00205023339
 protein coding gene Chr4:139006871-139014553 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230015751
 protein coding gene Chr4:150844939-150852615 (-)
NOD/ShiLtJ ENSMUSG00190021122
 protein coding gene Chr4:140210451-140218130 (-)
NZO/HlLtJ ENSMUSG00225024408
 protein coding gene Chr4:154837671-154845353 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    FBXO44, F-box protein 44
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO44, F-box protein 44
  • Synonyms
    FBG3, FBX30, Fbx44, FBX6A, Fbxo6a
  • Links
    NCBI Gene ID: 93611
    UniProt: Q9H4M3

  • Chr Location
    1p36.22; chr1:11650618-11663327 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    608
  • Tissues
    7
  • cDNA Data
    32
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 230903 NCBI Gene Model | MGI Sequence Detail 7408 C57BL/6J ±  kb
transcript NM_173401 RefSeq | MGI Sequence Detail 1863 C57BL/6  
polypeptide Q8BK26 UniProt | EBI | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140508
References
more
  • Summaries
    All 48
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 15
  • Earliest
    J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory