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Atp11a Gene Detail
Summary
  • Symbol
    Atp11a
  • Name
    ATPase, class VI, type 11A
  • Synonyms
    4930558F19Rik, 9130422H11Rik, Ih, LOC100045280
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354735
    NCBI Gene: 50770
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr8:12757014-12868728 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      111715 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 5.73 cM, cytoband A2
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ATP11A, ATPase phospholipid transporting 11A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ATP11A, ATPase phospholipid transporting 11A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ATPIH, ATPIS
  • Links
    NCBI Gene ID: 23250
    neXtProt AC: NX_P98196
    UniProt: P98196

  • Chr Location
    13q34; chr13:112690034-112887168 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 75050
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ATP11A
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    57 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a conditional allele activated in muscle cells exhibit abnormal myoblast function in culture and abnormal skeletal muscle regeneration.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000020604 VEGA Gene Model | MGI Sequence Detail 111715 C57BL/6J ±  kb
    transcript OTTMUST00000048809 VEGA | MGI Sequence Detail 7443 Not Applicable  
    polypeptide OTTMUSP00000022483 VEGA | MGI Sequence Detail 1187 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      942 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 27
      cDNA 26
      Primer pair 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1922594, MGI:2146150
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:59384 Halleck MS, et al., Differential expression of putative transbilayer amphipath transporters. Physiol Genomics. 1999 Nov 11;1(3):139-50
    • Latest
      J:262981 Tsuchiya M, et al., Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation. Nat Commun. 2018 May 24;9(1):2049

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    09/18/2018
    MGI 6.12
    The Jackson Laboratory