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Slc25a13
Gene Detail
Symbol

Name
ID
Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
MGI:1354721
Synonyms
citrin, Ctrn
Feature Type
protein coding gene
Genetic Map
Chromosome 6
2.30 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:6041218-6217118 bp, - strand
From VEGA annotation of GRCm38

  175901 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22800  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: SLC25A13
Gene Tree: Slc25a13

Human
homologs
SLC25A13, solute carrier family 25 (aspartate/glutamate carrier), member 13
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10165
neXtProt AC: NX_Q9UJS0

Human Synonyms: ARALAR2, CITRIN, CTLN2

Human Chr (Location): 7q21.3; chr7:96120220-96322147 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human SLC25A13

Mutations,
alleles, and
phenotypes
All mutations/alleles(226) : Gene trapped(225) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene appear normal, healthy and fertile, although they have a number of metabolic defects.
 
Mutations Annotated to Human Diseases (1)   
Interactions
Slc25a13 interacts with 204 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (249)    Tissues (67)    Images (27)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 247
Northern blot 2
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc25a13    NEW 
Molecular
reagents
All nucleic(16) cDNA(14) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000042278 (Evidence)
Ensembl Gene Model ENSMUSG00000015112 (Evidence)
Entrez Gene 50799 (Evidence)
DFCI TC1575629
DoTS DT.101162755, DT.101197367, DT.527928
NIA Mouse Gene Index U027026
Consensus CDS Project CCDS39421.1
International Mouse Phenotyping Consortium Status Slc25a13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042278 VEGA Gene Model | MGI Sequence Detail 175901 C57BL/6J ±  kb
transcript OTTMUST00000111238 VEGA | MGI Sequence Detail 3067 Not Applicable 
polypeptide OTTMUSP00000062212 VEGA | MGI Sequence Detail 676 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(430 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
InterPro IPR023395 Mitochondrial carrier domain
InterPro IPR002067 Mitochondrial carrier protein
InterPro IPR018108 Mitochondrial substrate/solute carrier
Protein Ontology PR:000015008 calcium-binding mitochondrial carrier protein Aralar2
References
(Earliest) J:59976 Sinasac DS, et al., Genomic structure of the adult-onset type II citrullinemia gene, SLC25A13, and cloning and expression of its mouse homologue. Genomics. 1999 Dec 1;62(2):289-92
(Latest) J:221202 Boon AC, et al., A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice. BMC Genomics. 2014;15:1017
All references(50)
Disease annotation references (2)
Other
accession IDs
MGI:2141468

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory