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Fbh1 Gene Detail
Summary
  • Symbol
    Fbh1
  • Name
    F-box DNA helicase 1
  • Synonyms
    Fbx18, Fbxo18
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354699
    NCBI Gene: 50755
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:11747384-11782393 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 9.01 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354699
protein coding gene Chr2:11747384-11782396 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025348
protein coding gene Chr2:9166243-9207876 (-)
A/J MGP_AJ_G0025325
protein coding gene Chr2:8783017-8819597 (-)
AKR/J MGP_AKRJ_G0025294
protein coding gene Chr2:9093068-9131968 (-)
BALB/cJ MGP_BALBcJ_G0025321
protein coding gene Chr2:8772802-8808259 (-)
C3H/HeJ MGP_C3HHeJ_G0025081
protein coding gene Chr2:9003213-9037142 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025763
protein coding gene Chr2:9419502-9458439 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023178
protein coding gene Chr2:8211569-8245757 (-)
CAST/EiJ MGP_CASTEiJ_G0024544
protein coding gene Chr2:9044082-9078394 (-)
CBA/J MGP_CBAJ_G0025060
protein coding gene Chr2:9810807-9854358 (-)
DBA/2J MGP_DBA2J_G0025192
protein coding gene Chr2:8696493-8730684 (-)
FVB/NJ MGP_FVBNJ_G0025154
protein coding gene Chr2:8617482-8651914 (-)
LP/J MGP_LPJ_G0025278
protein coding gene Chr2:9085567-9123988 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025186
protein coding gene Chr2:9686247-9732680 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025821
protein coding gene Chr2:9012961-9047396 (-)
PWK/PhJ MGP_PWKPhJ_G0024295
protein coding gene Chr2:8675644-8710123 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024095
protein coding gene Chr2:9014640-9054771 (-)
WSB/EiJ MGP_WSBEiJ_G0024614
protein coding gene Chr2:9079961-9114296 (-)



Homology
more
  • Human Ortholog
    FBH1, F-box DNA helicase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBH1, F-box DNA helicase 1
  • Synonyms
    Fbx18, FBXO18, hFBH1
  • Links
    NCBI Gene ID: 84893
    neXtProt AC: NX_Q8NFZ0
    UniProt: Q8NFZ0

  • Chr Location
    10p15.1; chr10:5889572-5937594 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058594 Ensembl Gene Model | MGI Sequence Detail 35010 C57BL/6J ±  kb
transcript ENSMUST00000071564 Ensembl | MGI Sequence Detail 3567 Not Applicable  
polypeptide ENSMUSP00000071495 Ensembl | MGI Sequence Detail 1042 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 130
    cDNA 130

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139155
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory