About   Help   FAQ
Fgd3 Gene Detail
Summary
  • Symbol
    Fgd3
  • Name
    FYVE, RhoGEF and PH domain containing 3
  • Synonyms
    5830461L01Rik, ZFYVE5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353657
    NCBI Gene: 30938
  • Gene Overview
    MyGene.info: FGD3
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:49263110-49320469 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 25.18 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353657
protein coding gene Chr13:49261554-49320469 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020533
protein coding gene Chr13:48228813-48288950 (-)
A/J MGP_AJ_G0020487
protein coding gene Chr13:46514177-46572873 (-)
AKR/J MGP_AKRJ_G0020464
protein coding gene Chr13:47827561-47886256 (-)
BALB/cJ MGP_BALBcJ_G0020483
protein coding gene Chr13:46730138-46788662 (-)
C3H/HeJ MGP_C3HHeJ_G0020282
protein coding gene Chr13:47650576-47710817 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020916
protein coding gene Chr13:49682877-49743223 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018501
protein coding gene Chr13:44493085-44552024 (-)
CAST/EiJ MGP_CASTEiJ_G0019797
protein coding gene Chr13:47656730-47717913 (-)
CBA/J MGP_CBAJ_G0020243
protein coding gene Chr13:51737227-51795940 (-)
DBA/2J MGP_DBA2J_G0020365
protein coding gene Chr13:46039504-46098520 (-)
FVB/NJ MGP_FVBNJ_G0020344
protein coding gene Chr13:45557597-45621178 (-)
LP/J MGP_LPJ_G0020440
protein coding gene Chr13:48450219-48510516 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020373
protein coding gene Chr13:51444284-51506904 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020959
protein coding gene Chr13:47529048-47588798 (-)
PWK/PhJ MGP_PWKPhJ_G0019553
protein coding gene Chr13:46222538-46281764 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019381
protein coding gene Chr13:46231045-46295206 (-)
WSB/EiJ MGP_WSBEiJ_G0019859
protein coding gene Chr13:47841502-47904754 (-)



Homology
more
  • Human Ortholog
    FGD3, FYVE, RhoGEF and PH domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FGD3, FYVE, RhoGEF and PH domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ZFYVE5
  • Links
    NCBI Gene ID: 89846
    neXtProt AC: NX_Q5JSP0
    UniProt: Q5JSP0

  • Chr Location
    9q22.31; chr9:92947319-93036236 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 30938 NCBI Gene Model | MGI Sequence Detail 57360 C57BL/6J ±  kb
transcript NM_015759 RefSeq | MGI Sequence Detail 3110 C57BL/6  
polypeptide O88842 UniProt | EBI | MGI Sequence Detail 733 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1923341
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory