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Fgd3 Gene Detail
Summary
  • Symbol
    Fgd3
  • Name
    FYVE, RhoGEF and PH domain containing 3
  • Synonyms
    5830461L01Rik, ZFYVE5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353657
    NCBI Gene: 30938
  • Gene Overview
    MyGene.info: FGD3
Location & Maps
more
  • Sequence Map
    Chr13:49261554-49320311 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      58758 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 25.18 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    FGD3, FYVE, RhoGEF and PH domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FGD3, FYVE, RhoGEF and PH domain containing 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ZFYVE5
  • Links
    NCBI Gene ID: 89846
    neXtProt AC: NX_Q5JSP0

  • Chr Location
    9q22; chr9:92947319-93036236 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Fgd3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020966 VEGA Gene Model | MGI Sequence Detail 58758 C57BL/6J ±  kb
transcript OTTMUST00000049566 VEGA | MGI Sequence Detail 4698 Not Applicable  
polypeptide OTTMUSP00000022987 VEGA | MGI Sequence Detail 733 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    153 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1923341
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:60236 Pasteris NG, et al., Isolation, characterization, and mapping of the mouse Fgd3 gene, a new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue. Gene. 2000 Jan 25;242(1-2):237-47
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory