Slc7a9
Gene Detail

Symbol Name ID

Slc7a9 solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 MGI:1353656

Synonyms

b, + amino acid transporter, b, +AT, CSNU3

Feature Type

protein coding gene

Genetic Map

Chromosome 7

21.37 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:35449037-35466036 bp, + strand From VEGA annotation of GRCm38   17000 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:56668  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: amino acid transporter
Gene Tree: Slc7a9

Human homologs

Human Homolog		SLC7A9, solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9
NCBI Gene ID		11136
neXtProt AC		NX_P82251
Human Synonyms		BAT1, CSNU3
Human Chr (Location)		19q13.1; chr19:33321417-33360683 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SLC7A9

Alleles and phenotypes

All alleles(4) : Targeted(1) Gene trapped(3)
 

Inactivation of this locus leads to renal absorption defects and cystine urolithiasis, similar to the symptoms observed in patients with cystinuria.

 
Human Diseases Modeled Using Mouse Slc7a9 (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	amino acid transmembrane transport, amino acid transport, ...
Component	integral to membrane, membrane
Function	amino acid transmembrane transporter activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (10)    Tissues (3)    Images (10)
Theiler Stages: 23

Assay Type	Results
RNA in situ	10

cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(18) cDNA(18)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000031618 (Evidence)
Ensembl Gene Model	ENSMUSG00000030492 (Evidence)
Entrez Gene	30962 (Evidence)
UniGene	45874
DFCI	TC1582925
DoTS	DT.110982174, DT.40177938, DT.91446987, DT.94181068
NIA Mouse Gene Index	U007969
Consensus CDS Project	CCDS21150.1
International Mouse Knockout Project Status	Slc7a9

Sequences

Length	Strain/Species
genomic	OTTMUSG00000031618	VEGA Gene Model | MGI Sequence Detail	17000	C57BL/6J
transcript	OTTMUST00000078326	VEGA | MGI Sequence Detail	1765	Not Applicable
polypeptide	OTTMUSP00000041640	VEGA | MGI Sequence Detail	487	Not Applicable

All sequences(47) RefSeq(6) UniProt(3)

Polymorphisms

SNPs(100 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002293	Amino acid/polyamine transporter I
Protein Ontology	PR:000015206	B(0,+)-type amino acid transporter 1

References

(Earliest) J:58992 Pfeiffer R, et al., Luminal heterodimeric amino acid transporter defective in cystinuria. Mol Biol Cell. 1999 Dec;10(12):4135-47
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(28)