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Prss30 Gene Detail
Summary
  • Symbol
    Prss30
  • Name
    protease, serine 30
  • Synonyms
    2010015P21Rik, Disp, Disp1, Tmprss8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353645
    NCBI Gene: 30943
Location & Maps
more
  • Sequence Map
    Chr17:23972126-23975230 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3105 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.17 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PRSS30P, protease, serine, 30 pseudogene
  • Vertebrate Orthologs
    4
  • Human Ortholog
    PRSS30P, protease, serine, 30 pseudogene
    Orthology source: HGNC
  • Synonyms
    Disp, TMPRSS8, TMPRSS8P
  • Links
    NCBI Gene ID: 124221

  • Chr Location
    16p13.3; chr16:2839573-2842751 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    1
  • Targeted
    1
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023161 VEGA Gene Model | MGI Sequence Detail 3105 C57BL/6J ±  kb
transcript OTTMUST00000056001 VEGA | MGI Sequence Detail 1470 Not Applicable  
polypeptide OTTMUSP00000026871 VEGA | MGI Sequence Detail 310 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    97 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016930 transmembrane serine protease 8
  • EC
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 26
    Genomic 1
    cDNA 24
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916446
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:60241 Shaw-Smith CJ, et al., Characterisation of a novel murine intestinal serine protease, DISP. Biochim Biophys Acta. 2000 Jan 31;1490(1-2):131-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory