Prss30
Gene Detail

Symbol Name ID

Prss30 protease, serine, 30 MGI:1353645

Synonyms

2010015P21Rik, Disp, Disp1, Tmprss8

Feature Type

protein coding gene

Genetic Map

Chromosome 17

12.17 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:23972126-23975230 bp, - strand From VEGA annotation of GRCm38   3105 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:88826  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: trypsin
Gene Tree: Prss30

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	ion transport, metabolic process, ...
Component	anchored to membrane, membrane, ...
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (20)    Tissues (20)    Images (1)
Theiler Stages: 10, 18, 23, 25, 28

Assay Type	Results
RT-PCR	20

cDNA source data(24)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(26) Genomic(1) cDNA(24) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000023161 (Evidence)
Ensembl Gene Model	ENSMUSG00000024124 (Evidence)
Entrez Gene	30943 (Evidence)
UniGene	142568
DFCI	TC1585823
DoTS	DT.525078
NIA Mouse Gene Index	U037513
EC	3.4.21.-
Consensus CDS Project	CCDS28470.1
International Mouse Knockout Project Status	Prss30

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023161	VEGA Gene Model | MGI Sequence Detail	3105	C57BL/6J
transcript	OTTMUST00000056001	VEGA | MGI Sequence Detail	1470	Not Applicable
polypeptide	OTTMUSP00000026871	VEGA | MGI Sequence Detail	310	Not Applicable

All sequences(35) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(32 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000016930	transmembrane serine protease 8

References

(Earliest) J:60241 Shaw-Smith CJ, et al., Characterisation of a novel murine intestinal serine protease, DISP. Biochim Biophys Acta. 2000 Jan 31;1490(1-2):131-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Other accession IDs

MGI:1916446