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Abt1 Gene Detail
Summary
  • Symbol
    Abt1
  • Name
    activator of basal transcription 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353636
    NCBI Gene: 30946
Location & Maps
more
  • Sequence Map
    Chr13:23421539-23423866 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2328 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.65 cM, cytoband A3.2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ABT1, activator of basal transcription 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ABT1, activator of basal transcription 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hABT1
  • Links
    NCBI Gene ID: 29777
    neXtProt AC: NX_Q9ULW3

  • Chr Location
    6p22.2; chr6:26596943-26600050 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Abt1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000736 VEGA Gene Model | MGI Sequence Detail 2328 C57BL/6J ±  kb
transcript OTTMUST00000001382 VEGA | MGI Sequence Detail 1278 Not Applicable  
polypeptide OTTMUSP00000000657 VEGA | MGI Sequence Detail 269 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    56 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000003591 activator of basal transcription 1
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
Molecular
Reagents
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  • All nucleic 62
    cDNA 61
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:60220 Oda T, et al., A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth. Mol Cell Biol. 2000 Feb;20(4):1407-18
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory