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Adat1
Gene Detail
Symbol

Name
ID
Adat1
adenosine deaminase, tRNA-specific 1
MGI:1353631
Synonyms
mADAT1
Feature Type
protein coding gene
Genetic Map
Chromosome 8
58.23 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:111966908-111992302 bp, - strand
From VEGA annotation of GRCm38

  25395 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8096  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ADAT1
Gene Tree: Adat1

Human
homologs
ADAT1, adenosine deaminase, tRNA-specific 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 23536
neXtProt AC: NX_Q9BUB4

Human Synonyms: HADAT1

Human Chr (Location): 16q23.1; chr16:75598349-75623323 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(14) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Adat1 interacts with 186 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process RNA processing, tRNA processing
Component cellular_component
Function adenosine deaminase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (93)    Tissues (93)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 93
cDNA source data(22)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase adat1    NEW 
Molecular
reagents
All nucleic(24) cDNA(23) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000029927 (Evidence)
Ensembl Gene Model ENSMUSG00000031949 (Evidence)
Entrez Gene 30947 (Evidence)
UniGene 282162
DFCI TC1602992, TC1666837, TC1585760, TC1594238
DoTS DT.87036074, DT.101365157, DT.94180296
NIA Mouse Gene Index U030274
EC 3.5.4.34
Consensus CDS Project CCDS22684.1
International Mouse Phenotyping Consortium Status Adat1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029927 VEGA Gene Model | MGI Sequence Detail 25395 C57BL/6J ±  kb
transcript OTTMUST00000074252 VEGA | MGI Sequence Detail 3159 Not Applicable 
polypeptide OTTMUSP00000038571 VEGA | MGI Sequence Detail 499 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(216 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002466 Adenosine deaminase/editase
Protein Ontology PR:000003748 tRNA-specific adenosine deaminase 1
References
(Earliest) J:60373 Maas S, et al., Sequence, genomic organization and functional expression of the murine tRNA-specific adenosine deaminase ADAT1. Gene. 2000 Feb 8;243(1-2):59-66
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory