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Adat1 Gene Detail
Summary
  • Symbol
    Adat1
  • Name
    adenosine deaminase, tRNA-specific 1
  • Synonyms
    mADAT1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353631
    NCBI Gene: 30947
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:111966908-111992302 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 58.23 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    218 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353631
protein coding gene Chr8:111966897-111992311 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034151
protein coding gene Chr8:114805026-114833080 (-)
A/J MGP_AJ_G0034131
protein coding gene Chr8:110117886-110143875 (-)
AKR/J MGP_AKRJ_G0034058
protein coding gene Chr8:113362322-113389657 (-)
BALB/cJ MGP_BALBcJ_G0034125
protein coding gene Chr8:110296574-110320380 (-)
C3H/HeJ MGP_C3HHeJ_G0033836
protein coding gene Chr8:114070995-114095102 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034645
protein coding gene Chr8:118812910-118842154 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031587
protein coding gene Chr8:103189225-103213707 (-)
CAST/EiJ MGP_CASTEiJ_G0033163
protein coding gene Chr8:113715350-113742888 (-)
CBA/J MGP_CBAJ_G0033809
protein coding gene Chr8:122909571-122940892 (-)
DBA/2J MGP_DBA2J_G0033965
protein coding gene Chr8:109390163-109416076 (-)
FVB/NJ MGP_FVBNJ_G0033908
protein coding gene Chr8:108373975-108399018 (-)
LP/J MGP_LPJ_G0034054
protein coding gene Chr8:114959133-114985302 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033955
protein coding gene Chr8:125741126-125768586 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034663
protein coding gene Chr8:113351300-113376689 (-)
PWK/PhJ MGP_PWKPhJ_G0032865
protein coding gene Chr8:109001622-109028568 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032705
protein coding gene Chr8:112001095-112029949 (-)
WSB/EiJ MGP_WSBEiJ_G0033279
protein coding gene Chr8:114030541-114058716 (-)



Homology
more
  • Human Ortholog
    ADAT1, adenosine deaminase tRNA specific 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ADAT1, adenosine deaminase tRNA specific 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HADAT1
  • Links
    NCBI Gene ID: 23536
    neXtProt AC: NX_Q9BUB4
    UniProt: Q9BUB4

  • Chr Location
    16q23.1; chr16:75596879-75623323 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8096
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ADAT1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031949 Ensembl Gene Model | MGI Sequence Detail 25395 C57BL/6J ±  kb
transcript ENSMUST00000034427 Ensembl | MGI Sequence Detail 3159 Not Applicable  
polypeptide ENSMUSP00000034427 Ensembl | MGI Sequence Detail 499 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 24
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:60373 Maas S, et al., Sequence, genomic organization and functional expression of the murine tRNA-specific adenosine deaminase ADAT1. Gene. 2000 Feb 8;243(1-2):59-66
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory