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Tor1b Gene Detail
Summary
  • Symbol
    Tor1b
  • Name
    torsin family 1, member B
  • Synonyms
    2610016F05Rik, DQ1, torsinB
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353605
    NCBI Gene: 30934
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:30952959-30959015 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 21.76 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    68 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353605
protein coding gene Chr2:30952939-30963458 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025577
protein coding gene Chr2:29249367-29255423 (+)
A/J MGP_AJ_G0025555
protein coding gene Chr2:28058264-28064320 (+)
AKR/J MGP_AKRJ_G0025524
protein coding gene Chr2:29014994-29021050 (+)
BALB/cJ MGP_BALBcJ_G0025551
protein coding gene Chr2:28192083-28198139 (+)
C3H/HeJ MGP_C3HHeJ_G0025312
protein coding gene Chr2:28946811-28952867 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025996
protein coding gene Chr2:30194885-30200941 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023404
protein coding gene Chr2:26824484-26830566 (+)
CAST/EiJ MGP_CASTEiJ_G0024775
protein coding gene Chr2:28880618-28886594 (+)
CBA/J MGP_CBAJ_G0025289
protein coding gene Chr2:31268510-31274566 (+)
DBA/2J MGP_DBA2J_G0025422
protein coding gene Chr2:27837029-27843085 (+)
FVB/NJ MGP_FVBNJ_G0025385
protein coding gene Chr2:27678515-27684571 (+)
LP/J MGP_LPJ_G0025508
protein coding gene Chr2:29156760-29162816 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025415
protein coding gene Chr2:31054395-31060451 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026054
protein coding gene Chr2:28928565-28934620 (+)
PWK/PhJ MGP_PWKPhJ_G0024521
protein coding gene Chr2:27711315-27717370 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024322
protein coding gene Chr2:29073833-29079855 (+)
WSB/EiJ MGP_WSBEiJ_G0024842
protein coding gene Chr2:29103005-29109061 (+)



Homology
more
  • Human Ortholog
    TOR1B, torsin family 1 member B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TOR1B, torsin family 1 member B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DQ1
  • Links
    NCBI Gene ID: 27348
    neXtProt AC: NX_O14657
    UniProt: O14657

  • Chr Location
    9q34.11; chr9:129803143-129811424 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 56677
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TOR1B
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026848 Ensembl Gene Model | MGI Sequence Detail 6057 C57BL/6J ±  kb
transcript ENSMUST00000028199 Ensembl | MGI Sequence Detail 3039 Not Applicable  
polypeptide ENSMUSP00000028199 Ensembl | MGI Sequence Detail 336 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 1
    cDNA 16
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:1917464
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:60248 Ozelius LJ, et al., The TOR1A (DYT1) gene family and its role in early onset torsion dystonia. Genomics. 1999 Dec 15;62(3):377-84
  • Latest
    J:239116 Tanabe LM, et al., Neuronal Nuclear Membrane Budding Occurs during a Developmental Window Modulated by Torsin Paralogs. Cell Rep. 2016 Sep 20;16(12):3322-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory