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Tor1b Gene Detail
Summary
  • Symbol
    Tor1b
  • Name
    torsin family 1, member B
  • Synonyms
    2610016F05Rik, DQ1, torsinB
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353605
    NCBI Gene: 30934
Location & Maps
more
  • Sequence Map
    Chr2:30952959-30959015 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6057 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 21.76 cM, cytoband B
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TOR1B, torsin family 1 member B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TOR1B, torsin family 1 member B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DQ1
  • Links
    NCBI Gene ID: 27348
    neXtProt AC: NX_O14657

  • Chr Location
    9q34; chr9:129803148-129811284 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 56677
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TOR1B
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Gene trapped
    1
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011877 VEGA Gene Model | MGI Sequence Detail 6057 C57BL/6J ±  kb
transcript OTTMUST00000027995 VEGA | MGI Sequence Detail 3039 Not Applicable  
polypeptide OTTMUSP00000012698 VEGA | MGI Sequence Detail 336 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    68 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 1
    cDNA 14
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:1917464
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:60248 Ozelius LJ, et al., The TOR1A (DYT1) gene family and its role in early onset torsion dystonia. Genomics. 1999 Dec 15;62(3):377-84
  • Latest
    J:160544 Kim CE, et al., A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9861-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory