About   Help   FAQ
Lmo7 Gene Detail
Summary
  • Symbol
    Lmo7
  • Name
    LIM domain only 7
  • Synonyms
    FBXO20, LOC380928, mKIAA0858
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353586
    NCBI Gene: 380928
  • Gene Overview
    MyGene.info: LMO7
Location & Maps
more
  • Sequence Map
    Chr14:101729957-101934710 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      204754 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    LMO7, LIM domain 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LMO7, LIM domain 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FBX20, FBXO20, LOMP
  • Links
    NCBI Gene ID: 4008
    neXtProt AC: NX_Q8WWI1

  • Chr Location
    13q22.2; chr13:75620434-75859870 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 83924
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: LMO7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Targeted
    4
  • Genomic Mutations
    1 involving Lmo7
  • Incidental Mutations
Targeted mutations in this gene result in postnatal lethality, growth defects, skeletal muscle abnormalities and retinal defects reflective of retinal degeneration.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034688 VEGA Gene Model | MGI Sequence Detail 204754 C57BL/6J ±  kb
transcript OTTMUST00000088062 VEGA | MGI Sequence Detail 6092 Not Applicable  
polypeptide OTTMUSP00000047977 VEGA | MGI Sequence Detail 1699 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1279 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 14
    Primer pair 1
    Other 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2685760
References
more
  • Summaries
    All 37
    Developmental Gene Expression 8
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:193641 Nakano Y, et al., A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory