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Snai3 Gene Detail
Summary
  • Symbol
    Snai3
  • Name
    snail family zinc finger 3
  • Synonyms
    Smuc, Snail-related gene from muscle cells, Zfp293
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353563
    NCBI Gene: 30927
Location & Maps
more
  • Sequence Map
    Chr8:122454206-122460692 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6487 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 71.07 cM, cytoband E1
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SNAI3, snail family transcriptional repressor 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SNAI3, snail family transcriptional repressor 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SMUC, SNAIL3, Zfp293, ZNF293
  • Links
    NCBI Gene ID: 333929
    neXtProt AC: NX_Q3KNW1

  • Chr Location
    16q24.3; chr16:88677682-88686474 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8500
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SNAI3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 5 alleles in 4 genetic backgrounds
    17 phenotypes from multigenic genotypes
    5 phenotype references
Mice homozygous for a knock-out allele exhibit no abnormal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006587 Ensembl Gene Model | MGI Sequence Detail 6487 C57BL/6J ±  kb
transcript ENSMUST00000006762 Ensembl | MGI Sequence Detail 1589 Not Applicable  
polypeptide ENSMUSP00000006762 Ensembl | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    103 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015310 zinc finger protein SNAI3
  • InterPro Domains
    IPR007087 Zinc finger, C2H2
    IPR015880 Zinc finger, C2H2-like
    IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Molecular
Reagents
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  • All nucleic 17
    cDNA 17

    Microarray probesets 5
Other
Accession IDs
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MGI:2142599
References
more
  • Summaries
    All 38
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:59877 Kataoka H, et al., A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs. Nucleic Acids Res. 2000 Jan 15;28(2):626-33
  • Latest
    J:219190 Pioli PD, et al., Fatal autoimmunity results from the conditional deletion of Snai2 and Snai3. Cell Immunol. 2015 Feb 24;295(1):1-18

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory