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Mlf2 Gene Detail
Summary
  • Symbol
    Mlf2
  • Name
    myeloid leukemia factor 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353554
    NCBI Gene: 30853
Location & Maps
more
  • Sequence Map
    Chr6:124931386-124937238 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5853 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MLF2, myeloid leukemia factor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MLF2, myeloid leukemia factor 2
    Orthology source: HomoloGene
  • Synonyms
    NTN4
  • Links
    NCBI Gene ID: 8079
    neXtProt AC: NX_Q15773

  • Chr Location
    12p13; chr12:6747992-6753470 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 3968
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: MLF2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000056694 VEGA Gene Model | MGI Sequence Detail 5853 C57BL/6J ±  kb
transcript OTTMUST00000139930 VEGA | MGI Sequence Detail 1451 Not Applicable  
polypeptide OTTMUSP00000073400 VEGA | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    5 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000010441 myeloid leukemia factor 2
  • InterPro Domains
    IPR019376 Myeloid leukemia factor
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
Other
Accession IDs
less
MGI:1889801, MGI:2141560
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:220288 Choudhury KR, et al., Chaperone protein HYPK interacts with the first 17 amino acid region of Huntingtin and modulates mutant HTT-mediated aggregation and cytotoxicity. Biochem Biophys Res Commun. 2015 Jan 2;456(1):66-73

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory