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Sspn
Gene Detail
 Symbol
Name
ID
Sspn
sarcospan
MGI:1353511
Synonyms Krag
Feature Type protein coding gene
Genetic Map
Chromosome 6
77.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:145931641-145965223 bp, + strand
From VEGA annotation of GRCm38

  33583 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3727  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sspn

Human
homologs
Human Homolog SSPN, sarcospan
NCBI Gene ID 8082
neXtProt AC  NX_Q14714
Human Synonyms  DAGA5, KRAG, NSPN, SPN1, SPN2
Human Chr (Location)  12p11.2; chr12:26195336-26234777 (+)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted null mutation exhibit no discernable phenotype; mice are viable and fertile with normal muscle histology and physiology.
 
Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Component cell junction, integral component of membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (15)    Tissues (8)   
Theiler Stages: 1, 2, 3, 5, 26, 28
Assay TypeResults
Immunohistochemistry 1
RT-PCR 14
cDNA source data(41)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(46) Genomic(2) cDNA(41) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025460 (Evidence)
Ensembl Gene ModelENSMUSG00000030255 (Evidence)
Entrez Gene16651 (Evidence)
UniGene49689
DFCITC1581888, TC1638614
DoTSDT.528685
NIA Mouse Gene IndexU007571
Consensus CDS ProjectCCDS20698.1
International Mouse Knockout Project StatusSspn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025460 VEGA Gene Model | MGI Sequence Detail 33583 C57BL/6J ±  kb
transcript OTTMUST00000062688 VEGA | MGI Sequence Detail 4431 Not Applicable 
polypeptide OTTMUSP00000030952 VEGA | MGI Sequence Detail 216 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(7) UniProt(5)
Polymorphisms SNPs within 2kb(537 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007237 CD20-like
Protein Ontology PR:000015657 sarcospan
References (Earliest) J:12009 George DL, et al., Amplified DNA in Y1 mouse adrenal tumor cells: isolation of cDNAs complementary to an amplified c-Ki-ras gene and localization of homologous sequences to mouse chromosome 6. Nucleic Acids Res. 1984 Mar 26;12(6):2731-43
(Latest) J:187752 Marshall JL, et al., Dystrophin and utrophin expression require sarcospan: loss of alpha7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice. Hum Mol Genet. 2012 Oct 15;21(20):4378-93
All references(37)
Other
accession IDs
MGD-MRK-16701, MGI:99905

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory