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Baz1b
Gene Detail
 Symbol
Name
ID
Baz1b
bromodomain adjacent to zinc finger domain, 1B
MGI:1353499
Synonyms Wbscr9, WSTF
Feature Type protein coding gene
Genetic Map
Chromosome 5
75.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr5:135187264-135246129 bp, + strand
From VEGA annotation of GRCm38

  58866 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22651  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Baz1b

Human
homologs
Human Homolog BAZ1B, bromodomain adjacent to zinc finger domain, 1B
NCBI Gene ID 9031
neXtProt AC  NX_Q9UIG0
Human Synonyms  WBSCR10, WBSCR9, WSTF
Human Chr (Location)  7q11.23; chr7:73440398-73522298 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(29) : Chemically induced (ENU)(1) Gene trapped(23) Targeted(5)
Genomic Mutations involving Baz1b (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit postnatal lethality by P2, small size at birth, impaired double strand DNA repair, and heart defects. Mice heterozygous for a null allele exhibit hypercalcemia and heart defects. Mice homozygous for an ENU mutation exhibit craniofacial and skeletal defects.
 
Human Diseases Modeled Using Mouse Baz1b (1)    Alleles Annotated to Human Diseases(3)   
Interactions
Baz1b interacts with 305 markers (Mir1b, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process cellular response to DNA damage stimulus, chromatin assembly or disassembly, ...
Component condensed chromosome, nuclear replication fork, ...
Function ATP binding, chromatin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (205)    Tissues (191)    Images (19)
Theiler Stages: 2, 3, 4, 5, 10, 17, 18, 19, 21, 22, 23, 24, 25, 27, 28
Assay TypeResults
RNA in situ 185
Northern blot 12
RT-PCR 8
cDNA source data(138)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(147) Genomic(5) cDNA(139) Primer pair(3)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000017117 (Evidence)
Ensembl Gene ModelENSMUSG00000002748 (Evidence)
Entrez Gene22385 (Evidence)
UniGene40331
DFCITC1577249, TC1598179
DoTSDT.110649704, DT.60102924
NIA Mouse Gene IndexU006282
EC2.7.10.2
Consensus CDS ProjectCCDS19736.1
International Mouse Knockout Project StatusBaz1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017117 VEGA Gene Model | MGI Sequence Detail 58866 C57BL/6J ±  kb
transcript OTTMUST00000041455 VEGA | MGI Sequence Detail 6492 Not Applicable 
polypeptide OTTMUSP00000018605 VEGA | MGI Sequence Detail 1479 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(1)
Polymorphisms PCR(1) : SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
InterPro IPR018359 Bromodomain, conserved site
InterPro IPR018500 DDT domain, subgroup
InterPro IPR018501 DDT domain superfamily
InterPro IPR013136 WSTF/Acf1/Cbp146
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000004658 bromodomain adjacent to zinc finger domain protein 1B
References (Earliest) J:51602 Peoples RJ, et al., Identification of the WBSCR9 gene, encoding a novel transcriptional regulator, in the Williams-Beuren syndrome deletion at 7q11.23. Cytogenet Cell Genet. 1998;82(3-4):238-46
(Latest) J:201508 Daxinger L, et al., An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Genome Biol. 2013 Sep 11;14(9):R96
All references(61)
Disease annotation references (2)
Other
accession IDs
MGI:1329032, MGI:2141344

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory