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Slc25a3
Gene Detail
 Symbol
Name
ID
Slc25a3
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
MGI:1353498
Synonyms 5730556H19Rik, Phc
Feature Type protein coding gene
Genetic Map
Chromosome 10
45.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:91116574-91124059 bp, - strand
From VEGA annotation of GRCm38

  7486 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37649  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Slc25a3

Human
homologs
Human Homolog SLC25A3, solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
NCBI Gene ID 5250
neXtProt AC  NX_Q00325
Human Synonyms  PHC, PTP
Human Chr (Location)  12q23; chr12:98593625-98602000 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SLC25A3
Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(16) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc25a3 interacts with 257 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process transport
Component extracellular vesicular exosome, integral component of membrane, ...
Function protein complex binding, symporter activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (322)    Tissues (137)    Images (52)
Theiler Stages: 22, 26, 28
Assay TypeResults
RNA in situ 322
cDNA source data(696)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(699) cDNA(699)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000035180 (Evidence)
Ensembl Gene ModelENSMUSG00000061904 (Evidence)
Entrez Gene18674 (Evidence)
UniGene298
DFCITC1573673, TC1602013
DoTSDT.101309390, DT.101400223, DT.101720559, DT.55107601, DT.91326034, DT.94149399, DT.94149489, DT.94391731
NIA Mouse Gene IndexU032127
Consensus CDS ProjectCCDS24121.1
International Mouse Knockout Project StatusSlc25a3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035180 VEGA Gene Model | MGI Sequence Detail 7486 C57BL/6J ±  kb
transcript OTTMUST00000089607 VEGA | MGI Sequence Detail 1341 Not Applicable 
polypeptide OTTMUSP00000048997 VEGA | MGI Sequence Detail 358 Not Applicable 

For the selected sequences
All sequences(105) RefSeq(4) UniProt(7)
Polymorphisms SNPs within 2kb(94 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023395 Mitochondrial carrier domain
InterPro IPR018108 Mitochondrial substrate/solute carrier
Protein Ontology PR:000015026 phosphate carrier protein, mitochondrial
References (Earliest) J:15475 Harrigan MT, et al., Isolation and characterization of glucocorticoid- and cyclic AMP-induced genes in T lymphocytes. Mol Cell Biol. 1989 Aug;9(8):3438-46
(Latest) J:195239 Ahmed SM, et al., KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. J Cell Biol. 2012 Dec 10;199(6):951-67
All references(47)
Other
accession IDs
MGD-MRK-13291, MGI:1915351, MGI:97573

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory