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Slc25a3 Gene Detail
Summary
  • Symbol
    Slc25a3
  • Name
    solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
  • Synonyms
    5730556H19Rik, Phc
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353498
    NCBI Gene: 18674
  • Gene Overview
    MyGene.info: SLC25A3
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr10:91116574-91124059 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7486 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 45.60 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC25A3, solute carrier family 25 member 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SLC25A3, solute carrier family 25 member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    OK/SW-cl.48, PHC, PTP
  • Links
    NCBI Gene ID: 5250
    neXtProt AC: NX_Q00325
    UniProt: Q00325

  • Chr Location
    12q23.1; chr12:98593625-98602000 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000035180 VEGA Gene Model | MGI Sequence Detail 7486 C57BL/6J ±  kb
    transcript OTTMUST00000089607 VEGA | MGI Sequence Detail 1341 Not Applicable  
    polypeptide OTTMUSP00000048997 VEGA | MGI Sequence Detail 358 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      94 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 699
      cDNA 699

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-13291, MGI:1915351, MGI:97573
    References
    more
    • Summaries
      All 57
      Developmental Gene Expression 5
      Gene Ontology 9
      Phenotypes 16
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory