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Slc25a3 Gene Detail
Summary
  • Symbol
    Slc25a3
  • Name
    solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
  • Synonyms
    5730556H19Rik, Phc
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353498
    NCBI Gene: 18674
  • Gene Overview
    MyGene.info: SLC25A3
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:91116578-91124001 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 45.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    94 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353498
protein coding gene Chr10:91116574-91124059 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017644
protein coding gene Chr10:92405151-92413144 (-)
A/J MGP_AJ_G0017623
protein coding gene Chr10:89200650-89208728 (-)
AKR/J MGP_AKRJ_G0017581
protein coding gene Chr10:91762892-91770377 (-)
BALB/cJ MGP_BALBcJ_G0017586
protein coding gene Chr10:89483465-89490950 (-)
C3H/HeJ MGP_C3HHeJ_G0017409
protein coding gene Chr10:91781309-91788794 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018043
protein coding gene Chr10:95462443-95469928 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015725
protein coding gene Chr10:84870110-84877644 (-)
CAST/EiJ MGP_CASTEiJ_G0016974
protein coding gene Chr10:91707073-91715352 (-)
CBA/J MGP_CBAJ_G0017378
protein coding gene Chr10:99405051-99418640 (-)
DBA/2J MGP_DBA2J_G0017484
protein coding gene Chr10:88323823-88332911 (-)
FVB/NJ MGP_FVBNJ_G0017476
protein coding gene Chr10:87544636-87552424 (-)
LP/J MGP_LPJ_G0017558
protein coding gene Chr10:93039262-93046747 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017507
protein coding gene Chr10:100863970-100871476 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018080
protein coding gene Chr10:91649492-91656977 (-)
PWK/PhJ MGP_PWKPhJ_G0016755
protein coding gene Chr10:88379428-88390000 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016543
protein coding gene Chr10:90408282-90415741 (-)
WSB/EiJ MGP_WSBEiJ_G0017033
protein coding gene Chr10:91620284-91627773 (-)



Homology
more
  • Human Ortholog
    SLC25A3, solute carrier family 25 member 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SLC25A3, solute carrier family 25 member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    OK/SW-cl.48, PHC, PTP
  • Links
    NCBI Gene ID: 5250
    neXtProt AC: NX_Q00325
    UniProt: Q00325

  • Chr Location
    12q23.1; chr12:98593625-98602000 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 2 alleles in 2 genetic backgrounds
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 18674 NCBI Gene Model | MGI Sequence Detail 7424 C57BL/6J ±  kb
    transcript NM_133668 RefSeq | MGI Sequence Detail 1550 C57BL/6  
    polypeptide Q8VEM8 UniProt | EBI | MGI Sequence Detail 357 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 701
      cDNA 700
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-13291, MGI:1915351, MGI:97573
    References
    more
    • Summaries
      All 59
      Developmental Gene Expression 5
      Gene Ontology 10
      Phenotypes 18
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory