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Slc25a10
Gene Detail
Symbol

Name
ID
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
MGI:1353497
Synonyms
Dic
Feature Type
protein coding gene
Genetic Map
Chromosome 11
84.19 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:120491840-120499187 bp, + strand
From VEGA annotation of GRCm38

  7348 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6519  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc25a10

Human
homologs
Human Homolog SLC25A10, solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
NCBI Gene ID 1468
neXtProt AC  NX_Q9UBX3
Human Synonyms  DIC
Human Chr (Location)  17q25.3; chr17:81712236-81721016 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from APF )
Interactions
Slc25a10 interacts with 137 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process malate transmembrane transport, malate transport, ...
Component cell, integral component of membrane, ...
Function antiporter activity, malate transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (21)    Tissues (5)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 20
cDNA source data(161)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(164) cDNA(162) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000004270 (Evidence)
Ensembl Gene ModelENSMUSG00000025792 (Evidence)
Entrez Gene27376 (Evidence)
UniGene3991
DFCITC1602920, TC1574497
DoTSDT.492527
NIA Mouse Gene IndexU013664
Consensus CDS ProjectCCDS25738.1
International Mouse Knockout Project StatusSlc25a10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004270 VEGA Gene Model | MGI Sequence Detail 7348 C57BL/6J ±  kb
transcript OTTMUST00000009677 VEGA | MGI Sequence Detail 2023 Not Applicable 
polypeptide OTTMUSP00000004662 VEGA | MGI Sequence Detail 287 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(16 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002030 Mitochondrial brown fat uncoupling protein
InterPro IPR023395 Mitochondrial carrier domain
InterPro IPR018108 Mitochondrial substrate/solute carrier
Protein Ontology PR:000015005 mitochondrial dicarboxylate carrier
References
(Earliest) J:58915 Das K, et al., Predominant expression of the mitochondrial dicarboxylate carrier in white adipose tissue. Biochem J. 1999 Dec 1;344 Pt 2:313-20
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)
Other
accession IDs
MGI:1351621

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory