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Slc25a5
Gene Detail
Symbol

Name
ID
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
MGI:1353496
Synonyms
adenine nucleotide translocase, Ant2
Feature Type
protein coding gene
Genetic Map
Chromosome X
21.20 cM, cytoband A4
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
ChrX:36795651-36798807 bp, + strand
From VEGA annotation of GRCm38

  3157 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55557  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC25A5
Gene Tree: Slc25a5

Human
homologs
SLC25A5, solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 292
neXtProt AC: NX_P05141

Human Synonyms: 2F1, AAC2, ANT2, T2, T3

Human Chr (Location): Xq24; chrX:119468400-119471396 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc25a5 interacts with 79 markers (Mir1b, Mir32, Mir92-1, ...)
Expression
Literature Summary: (9 records)
Data Summary: Results (58)    Tissues (56)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 56
RT-PCR 2
cDNA source data(17)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc25a5    NEW 
Molecular
reagents
All nucleic(26) Genomic(4) cDNA(18) Primer pair(4)
Microarray probesets(11)
Other database
links
VEGA Gene Model OTTMUSG00000016520 (Evidence)
Ensembl Gene Model ENSMUSG00000016319 (Evidence)
Entrez Gene 11740 (Evidence)
DFCI TC1573755, TC1659105, TC1733518
DoTS DT.101150243, DT.101398750, DT.101398756, DT.102546916, DT.537544, DT.94387143
Consensus CDS Project CCDS30062.1
International Mouse Phenotyping Consortium Status Slc25a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016520 VEGA Gene Model | MGI Sequence Detail 3157 C57BL/6J ±  kb
transcript OTTMUST00000039927 VEGA | MGI Sequence Detail 1240 Not Applicable 
polypeptide OTTMUSP00000017802 VEGA | MGI Sequence Detail 298 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(2) UniProt(3)
Polymorphisms
All PCR and RFLP(3) : PCR(2) RFLP(1) SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002113 Adenine nucleotide translocator 1
InterPro IPR023395 Mitochondrial carrier domain
InterPro IPR002067 Mitochondrial carrier protein
InterPro IPR018108 Mitochondrial substrate/solute carrier
Protein Ontology PR:000015033 ADP/ATP translocase 2
References
(Earliest) J:41737 Cozens AL, et al., DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. J Mol Biol. 1989 20;206(2):261-80
(Latest) J:214695 Markkanen M, et al., Distribution of neuronal KCC2a and KCC2b isoforms in mouse CNS. J Comp Neurol. 2014 Jun 1;522(8):1897-914
All references(52)
Other
accession IDs
MGD-MRK-33602, MGI:105924

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory