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Slc25a5 Gene Detail
Summary
  • Symbol
    Slc25a5
  • Name
    solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
  • Synonyms
    adenine nucleotide translocase, Ant2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353496
    NCBI Gene: 11740
  • Gene Overview
    MyGene.info: SLC25A5
Location & Maps
more
  • Sequence Map
    ChrX:36795651-36798807 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3157 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 21.20 cM, cytoband A4
  • Mapping Data
    13 experiments
Homology
more
  • Human Ortholog
    SLC25A5, solute carrier family 25 member 5
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC25A5, solute carrier family 25 member 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    2F1, AAC2, ANT2, T2, T3
  • Links
    NCBI Gene ID: 292
    neXtProt AC: NX_P05141

  • Chr Location
    Xq24; chrX:119468400-119471396 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from multigenic genotypes
    5 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    3
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016520 VEGA Gene Model | MGI Sequence Detail 3157 C57BL/6J ±  kb
transcript OTTMUST00000039927 VEGA | MGI Sequence Detail 1240 Not Applicable  
polypeptide OTTMUSP00000017802 VEGA | MGI Sequence Detail 298 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    13 from dbSNP Build 142
  • PCR
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    Genomic 4
    cDNA 18
    Primer pair 4

    Microarray probesets 11
Other
Accession IDs
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MGD-MRK-33602, MGI:105924
References
more
  • Summaries
    All 51
    Developmental Gene Expression 9
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:41737 Cozens AL, et al., DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. J Mol Biol. 1989 20;206(2):261-80
  • Latest
    J:234617 Cho J, et al., Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis. Cell Death Differ. 2015 Sep;22(9):1437-50

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory