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Slc25a5
Gene Detail
Symbol

Name
ID
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
MGI:1353496
Synonyms
adenine nucleotide translocase, Ant2
Feature Type
protein coding gene
Genetic Map
Chromosome X
21.20 cM, cytoband A4
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
ChrX:36795651-36798807 bp, + strand
From VEGA annotation of GRCm38

  3157 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55557  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc25a5

Human
homologs
Human Homolog SLC25A5, solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
NCBI Gene ID 292
neXtProt AC  NX_P05141
Human Synonyms  2F1, AAC2, ANT2, T2, T3
Human Chr (Location)  Xq24; chrX:119468400-119471396 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc25a5 interacts with 79 markers (Mir1b, Mir32, Mir92-1, ...)
Expression
Literature Summary: (8 records)
Data Summary: Results (58)    Tissues (56)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 56
RT-PCR 2
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) Genomic(4) cDNA(18) Primer pair(4)
Microarray probesets(11)
Other database
links
VEGA Gene ModelOTTMUSG00000016520 (Evidence)
Ensembl Gene ModelENSMUSG00000016319 (Evidence)
Entrez Gene11740 (Evidence)
DFCITC1573755, TC1659105, TC1733518
DoTSDT.101150243, DT.101398750, DT.101398756, DT.102546916, DT.537544, DT.94387143
Consensus CDS ProjectCCDS30062.1
International Mouse Knockout Project StatusSlc25a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016520 VEGA Gene Model | MGI Sequence Detail 3157 C57BL/6J ±  kb
transcript OTTMUST00000039927 VEGA | MGI Sequence Detail 1240 Not Applicable 
polypeptide OTTMUSP00000017802 VEGA | MGI Sequence Detail 298 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(2) UniProt(3)
Polymorphisms
All PCR and RFLP(3) : PCR(2) RFLP(1) SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002113 Adenine nucleotide translocator 1
InterPro IPR023395 Mitochondrial carrier domain
InterPro IPR002067 Mitochondrial carrier protein
InterPro IPR018108 Mitochondrial substrate/solute carrier
Protein Ontology PR:000015033 ADP/ATP translocase 2
References
(Earliest) J:41737 Cozens AL, et al., DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. J Mol Biol. 1989 20;206(2):261-80
(Latest) J:183237 Loers G, et al., The interaction between cell adhesion molecule L1, matrix metalloproteinase 14, and adenine nucleotide translocator at the plasma membrane regulates L1-mediated neurite outgrowth of murine cerebellar neurons. J Neurosci. 2012 Mar 14;32(11):3917-30
All references(51)
Other
accession IDs
MGD-MRK-33602, MGI:105924

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory