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Airn Gene Detail
Summary
  • Symbol
    Airn
  • Name
    antisense Igf2r RNA
  • Synonyms
    2810051F02Rik, 2810434M15Rik, Air, B930018I07Rik, D17Ertd663e
Location &
Maps
more
  • Sequence Map
    Chr17:12741311-12859884 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 8.66 cM
  • Mapping Data
    7 experiments
Strain
Comparison
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  • SNPs within 2kb
    375 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353471
antisense lncRNA gene Chr17:12741311-12860136 (+)
129S1/SvImJ MGP_129S1SvImJ_G0003371
antisense lncRNA gene Chr17:10405514-10527068 (+)
A/J MGP_AJ_G0003347
antisense lncRNA gene Chr17:10235680-10358024 (+)
AKR/J MGP_AKRJ_G0003330
antisense lncRNA gene Chr17:10062198-10189195 (+)
BALB/cJ MGP_BALBcJ_G0003336
antisense lncRNA gene Chr17:10010437-10131682 (+)
C3H/HeJ MGP_C3HHeJ_G0003289
antisense lncRNA gene Chr17:10310285-10435842 (+)
C57BL/6NJ MGP_C57BL6NJ_G0003477
antisense lncRNA gene Chr17:10797738-10927909 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002991
antisense lncRNA gene Chr17:4091146-4210110 (-)
CAST/EiJ MGP_CASTEiJ_G0003252
antisense lncRNA gene Chr17:10393505-10518302 (+)
CBA/J MGP_CBAJ_G0003285
antisense lncRNA gene Chr17:11202019-11345168 (+)
DBA/2J MGP_DBA2J_G0003291
antisense lncRNA gene Chr17:9878305-9998519 (+)
FVB/NJ MGP_FVBNJ_G0003309
antisense lncRNA gene Chr17:9814582-9934461 (+)
LP/J MGP_LPJ_G0003364
antisense lncRNA gene Chr17:10223980-10358105 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0003298
antisense lncRNA gene Chr17:10804504-10930453 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0003480
antisense lncRNA gene Chr17:10331943-10462492 (+)
PWK/PhJ MGP_PWKPhJ_G0003212
antisense lncRNA gene Chr17:9564619-9686552 (+)
SPRET/EiJ MGP_SPRETEiJ_G0003156
antisense lncRNA gene Chr17:9762192-9894574 (+)
WSB/EiJ MGP_WSBEiJ_G0003286
antisense lncRNA gene Chr17:10651247-10774187 (+)



Homology
more
  • Human Ortholog
    AIRN, antisense of IGF2R non-protein coding RNA
  • Human Ortholog
    AIRN, antisense of IGF2R non-protein coding RNA
    Orthology source: HGNC
  • Synonyms
    AIR, IGF2RAS, IGF2R-AS, IGF2R-AS1, NCRNA00088
  • Links
    NCBI Gene ID: 100271873

  • Chr Location
    6q25.3; chr6:160003291-160007664 (-)  GRCh38.p7

  • HCOP
    human homology predictions: AIRN
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Whereas heterozygous mice carrying a maternally inherited allele showed no overt phenotype, heterozygous mice carrying a paternally inherited allele and homozygous mice exhibited reduced body weight at birth.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    • All Sequences
    • RefSeq
    • UniProt
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 104103 NCBI Gene Model | MGI Sequence Detail 118574 C57BL/6J ±  kb
    transcript NR_027784 RefSeq | MGI Sequence Detail 1399 C57BL/6  
    polypeptide Q78TB4 UniProt | EBI | MGI Sequence Detail 109 Not Applicable  
    For the selected sequence
    Protein
    Information
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    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 40
      Genomic 1
      cDNA 27
      Primer pair 12

      Microarray probesets 6
    Other
    Accession IDs
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    MGI:1289299, MGI:1917228, MGI:1919954, MGI:2146811, MGI:2146894, MGI:2147040, MGI:2443603
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 14
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:43503 Wutz A, et al., Imprinted expression of the Igf2r gene depends on an intronic CpG island [see comments]. Nature. 1997 Oct 16;389(6652):745-9
    • Latest
      J:279720 Andergassen D, et al., The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes. PLoS Genet. 2019 Jul;15(7):e1008268

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    last database update
    09/22/2020
    MGI 6.16
    The Jackson Laboratory