Pdlim4
Gene Detail

Symbol Name ID

Pdlim4 PDZ and LIM domain 4 MGI:1353470

Synonyms

Ril

Feature Type

protein coding gene

Genetic Map

Chromosome 11

32.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr11:54054928-54069014 bp, - strand From VEGA annotation of GRCm38   14087 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2735  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: PDZ and LIM domain protein
Gene Tree: Pdlim4

Human homologs

Human Homolog		PDLIM4, PDZ and LIM domain 4
NCBI Gene ID		8572
neXtProt AC		NX_P50479
Human Synonyms		RIL
Human Chr (Location)		5q31.1; chr5:131593351-131609147 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human PDLIM4

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (2 annotations)

Function

metal ion binding, zinc ion binding

External Resources: FuncBase

Expression

Literature Summary: (10 records)
Data Summary: Results (301)    Tissues (102)    Images (29)
Theiler Stages: 11, 13, 15, 17, 18, 19, 21, 23, 28

Assay Type	Results
RNA in situ	301

cDNA source data(40)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(42) Genomic(2) cDNA(40)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000005656 (Evidence)
Ensembl Gene Model	ENSMUSG00000020388 (Evidence)
Entrez Gene	30794 (Evidence)
UniGene	21830
DFCI	TC1579660, TC1590843
DoTS	DT.490007, DT.94306918
NIA Mouse Gene Index	U032775
Consensus CDS Project	CCDS24690.1
International Mouse Knockout Project Status	Pdlim4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000005656	VEGA Gene Model | MGI Sequence Detail	14087	C57BL/6J
transcript	OTTMUST00000012586	VEGA | MGI Sequence Detail	1182	Not Applicable
polypeptide	OTTMUSP00000005828	VEGA | MGI Sequence Detail	330	Not Applicable

All sequences(35) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(69 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001478	PDZ domain
InterPro	IPR001781	Zinc finger, LIM-type
Protein Ontology	PR:000029668	PDZ and LIM domain protein 4

References

(Earliest) J:60685 Kiess M, et al., Expression of ril, a novel LIM domain gene, is down-regulated in Hras-transformed cells and restored in phenotypic revertants. Oncogene. 1995 Jan 5;10(1):61-8
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(36)