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Pdlim4
Gene Detail
 Symbol
Name
ID
Pdlim4
PDZ and LIM domain 4
MGI:1353470
Synonyms Ril
Feature Type protein coding gene
Genetic Map
Chromosome 11
32.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:54054928-54069014 bp, - strand
From VEGA annotation of GRCm38

  14087 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2735  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: PDZ and LIM domain protein
Gene Tree: Pdlim4

Human
homologs
Human Homolog PDLIM4, PDZ and LIM domain 4
NCBI Gene ID 8572
neXtProt AC  NX_P50479
Human Synonyms  RIL
Human Chr (Location)  5q31.1; chr5:132257658-132273454 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PDLIM4
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Pdlim4 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pdlim4 interacts with 30 markers (Mir15a, Mir27a, Mir27b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process actin cytoskeleton organization
Function actinin binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (301)    Tissues (102)    Images (29)
Theiler Stages: 11, 13, 15, 17, 18, 19, 21, 23, 27
Assay TypeResults
RNA in situ 301
cDNA source data(40)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(42) Genomic(2) cDNA(40)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000005656 (Evidence)
Ensembl Gene ModelENSMUSG00000020388 (Evidence)
Entrez Gene30794 (Evidence)
UniGene21830
DFCITC1579660, TC1590843
DoTSDT.490007, DT.94306918
NIA Mouse Gene IndexU032775
Consensus CDS ProjectCCDS24690.1
International Mouse Knockout Project StatusPdlim4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005656 VEGA Gene Model | MGI Sequence Detail 14087 C57BL/6J ±  kb
transcript OTTMUST00000012586 VEGA | MGI Sequence Detail 1182 Not Applicable 
polypeptide OTTMUSP00000005828 VEGA | MGI Sequence Detail 330 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(110 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001478 PDZ domain
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000029668 PDZ and LIM domain protein 4
References (Earliest) J:60685 Kiess M, et al., Expression of ril, a novel LIM domain gene, is down-regulated in Hras-transformed cells and restored in phenotypic revertants. Oncogene. 1995 Jan 5;10(1):61-8
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory