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Fkbp3 Gene Detail
Summary
  • Symbol
    Fkbp3
  • Name
    FK506 binding protein 3
  • Synonyms
    25kDa, FKBP25
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353460
    NCBI Gene: 30795
  • Gene Overview
    MyGene.info: FKBP3
Location & Maps
more
  • Sequence Map
    Chr12:65062432-65073938 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11507 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    FKBP3, FK506 binding protein 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FKBP3, FK506 binding protein 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FKBP25, FKBP-25, FKBP-3, PPIase
  • Links
    NCBI Gene ID: 2287
    neXtProt AC: NX_Q00688

  • Chr Location
    14q21.2; chr14:45115599-45134529 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    45
  • Chemically induced (other)
    1
  • Gene trapped
    42
  • Targeted
    2
  • Genomic Mutations
    1 involving Fkbp3
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 30795 NCBI Gene Model | MGI Sequence Detail 11507 C57BL/6J ±  kb
transcript NM_013902 RefSeq | MGI Sequence Detail 945 C57BL/6  
polypeptide Q62446 UniProt | EBI | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    100 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000007539 peptidyl-prolyl cis-trans isomerase FKBP3
  • PDB
  • EC
  • InterPro Domains
    IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain
    IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type
Molecular
Reagents
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  • All nucleic 121
    cDNA 118
    Primer pair 3

    Microarray probesets 4
References
more
  • Summaries
    All 44
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:62503 Murphy M, et al., Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes Dev. 1996 Dec 1;10(23):2971-80
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory