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Aldh3a2
Gene Detail
 Symbol
Name
ID
Aldh3a2
aldehyde dehydrogenase family 3, subfamily A2
MGI:1353452
Synonyms Ahd3, Ahd-3, Ahd-3r, Ahd3-r, Aldh4, Aldh4-r, FALDH
Feature Type protein coding gene
Genetic Map
Chromosome 11
37.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)
Sequence Map
Chr11:61223417-61267464 bp, - strand
From VEGA annotation of GRCm38

  44048 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55458  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: aldehyde dehydrogenase
Gene Tree: Aldh3a2

Human
homologs
Human Homolog ALDH3A2, aldehyde dehydrogenase 3 family, member A2
NCBI Gene ID 224
neXtProt AC  NX_P51648
Human Synonyms  ALDH10, FALDH, SLS
Human Chr (Location)  17p11.2; chr17:19648751-19677595 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALDH3A2
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(5) Targeted(7)
Genomic Mutations involving Aldh3a2 (2)
Incidental mutations (data from Mutagenetix , APF )
Alleles Annotated to Human Diseases(2)   
Interactions
Aldh3a2 interacts with 249 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process cellular aldehyde metabolic process, central nervous system development, ...
Component cytosol, endoplasmic reticulum, ...
Function 3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (119)    Tissues (105)    Images (19)
Theiler Stages: 1, 3, 4, 22, 23, 28
Assay TypeResults
RNA in situ 110
RT-PCR 9
cDNA source data(113)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(117) cDNA(115) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000005829 (Evidence)
Ensembl Gene ModelENSMUSG00000010025 (Evidence)
Entrez Gene11671 (Evidence)
UniGene398221
DFCITC1573405
DoTSDT.55255763, DT.91405517, DT.94239148, DT.94293465
NIA Mouse Gene IndexU032880
EC1.2.1.3
Consensus CDS ProjectCCDS24809.1
International Mouse Knockout Project StatusAldh3a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005829 VEGA Gene Model | MGI Sequence Detail 44048 C57BL/6J ±  kb
transcript OTTMUST00000012932 VEGA | MGI Sequence Detail 2892 Not Applicable 
polypeptide OTTMUSP00000006017 VEGA | MGI Sequence Detail 532 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(12) UniProt(5)
Polymorphisms RFLP(2) : SNPs within 2kb(432 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016160 Aldehyde dehydrogenase, conserved site
InterPro IPR016163 Aldehyde dehydrogenase, C-terminal
InterPro IPR015590 Aldehyde dehydrogenase domain
InterPro IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
InterPro IPR016162 Aldehyde dehydrogenase, N-terminal
InterPro IPR016161 Aldehyde/histidinol dehydrogenase
Protein Ontology PR:000003927 fatty aldehyde dehydrogenase
References (Earliest) J:6570 Timms GP, et al., Genetics of aldehyde dehydrogenase isozymes in the mouse: evidence for multiple loci and localization of Ahd-2 on chromosome 19. Genetics. 1981 Feb;97(2):327-36
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(61)
Other
accession IDs
MGD-MRK-1207, MGD-MRK-1208, MGD-MRK-1214, MGD-MRK-1215, MGD-MRK-16379, MGD-MRK-16380, MGI:2144079, MGI:99597, MGI:99598

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory