Aldh3a2
Gene Detail

Symbol Name ID

Aldh3a2 aldehyde dehydrogenase family 3, subfamily A2 MGI:1353452

Synonyms

Ahd3, Ahd-3, Ahd-3r, Ahd3-r, Aldh4, Aldh4-r, FALDH

Feature Type

protein coding gene

Genetic Map

Chromosome 11

37.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)

Sequence Map

Chr11:61223417-61267464 bp, - strand From VEGA annotation of GRCm38   44048 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55458  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: aldehyde dehydrogenase
Gene Tree: Aldh3a2

Human homologs

Human Homolog		ALDH3A2, aldehyde dehydrogenase 3 family, member A2
NCBI Gene ID		224
neXtProt AC		NX_P51648
Human Synonyms		ALDH10, FALDH, SLS
Human Chr (Location)		17p11.2; chr17:19552064-19580908 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ALDH3A2

Alleles and phenotypes

All alleles(10) : Targeted(5) Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (30 annotations)

Process	cellular aldehyde metabolic process, central nervous system development, ...
Component	cytosol, endoplasmic reticulum, ...
Function	3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (119)    Tissues (105)    Images (19)
Theiler Stages: 1, 3, 4, 22, 23, 28

Assay Type	Results
RNA in situ	110
RT-PCR	9

cDNA source data(112)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(116) cDNA(114) Primer pair(2)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000005829 (Evidence)
Ensembl Gene Model	ENSMUSG00000010025 (Evidence)
Entrez Gene	11671 (Evidence)
UniGene	398221
DFCI	TC1573405
DoTS	DT.55255763, DT.91405517, DT.94239148, DT.94293465
NIA Mouse Gene Index	U032880
EC	1.2.1.3
Consensus CDS Project	CCDS24809.1
International Mouse Knockout Project Status	Aldh3a2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000005829	VEGA Gene Model | MGI Sequence Detail	44048	C57BL/6J
transcript	OTTMUST00000012932	VEGA | MGI Sequence Detail	2892	Not Applicable
polypeptide	OTTMUSP00000006017	VEGA | MGI Sequence Detail	532	Not Applicable

All sequences(61) RefSeq(2) UniProt(5)

Polymorphisms

RFLP(2) : SNPs(220 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR016160	Aldehyde dehydrogenase, conserved site
InterPro	IPR016163	Aldehyde dehydrogenase, C-terminal
InterPro	IPR015590	Aldehyde dehydrogenase domain
InterPro	IPR012394	Aldehyde dehydrogenase NAD(P)-dependent
InterPro	IPR016162	Aldehyde dehydrogenase, N-terminal
InterPro	IPR016161	Aldehyde/histidinol dehydrogenase
Protein Ontology	PR:000003927	fatty aldehyde dehydrogenase

References

(Earliest) J:6570 Timms GP, et al., Genetics of aldehyde dehydrogenase isozymes in the mouse: evidence for multiple loci and localization of Ahd-2 on chromosome 19. Genetics. 1981 Feb;97(2):327-36
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(60)

Other accession IDs

MGD-MRK-1207, MGD-MRK-1208, MGD-MRK-1214, MGD-MRK-1215, MGD-MRK-16379, MGD-MRK-16380, MGI:2144079, MGI:99597, MGI:99598