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Aldh3a2
Gene Detail
Symbol

Name
ID
Aldh3a2
aldehyde dehydrogenase family 3, subfamily A2
MGI:1353452
Synonyms
Ahd3, Ahd-3, Ahd-3r, Ahd3-r, Aldh4, Aldh4-r, FALDH
Feature Type
protein coding gene
Genetic Map
Chromosome 11
37.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)
Sequence Map
Chr11:61223417-61267464 bp, - strand
From VEGA annotation of GRCm38

  44048 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55458  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: ALDH3A2
Protein SuperFamily: aldehyde dehydrogenase
Gene Tree: Aldh3a2

Human
homologs
ALDH3A2, aldehyde dehydrogenase 3 family, member A2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 224
neXtProt AC: NX_P51648

Human Synonyms: ALDH10, FALDH, SLS

Human Chr (Location): 17p11.2; chr17:19648136-19677596 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ALDH3A2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(5) Targeted(8)
Genomic Mutations involving Aldh3a2 (2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Mutations Annotated to Human Diseases (2)   
Interactions
Aldh3a2 interacts with 248 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (116)    Tissues (102)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 110
RT-PCR 6
cDNA source data(113)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA ALDH3A2 ; Xenbase aldh3a2 ; ZFIN aldh3a2a, aldh3a2b    NEW 
Molecular
reagents
All nucleic(117) cDNA(115) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000005829 (Evidence)
Ensembl Gene Model ENSMUSG00000010025 (Evidence)
Entrez Gene 11671 (Evidence)
UniGene 398221
DFCI TC1573405, TC1769209
DoTS DT.55255763, DT.91405517, DT.94239148, DT.94293465
NIA Mouse Gene Index U032880
EC 1.2.1.3
Consensus CDS Project CCDS24809.1
International Mouse Phenotyping Consortium Status Aldh3a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005829 VEGA Gene Model | MGI Sequence Detail 44048 C57BL/6J ±  kb
transcript OTTMUST00000012932 VEGA | MGI Sequence Detail 2892 Not Applicable 
polypeptide OTTMUSP00000006017 VEGA | MGI Sequence Detail 532 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(12) UniProt(5)
Polymorphisms
RFLP(2) : SNPs within 2kb(432 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016163 Aldehyde dehydrogenase, C-terminal
InterPro IPR016160 Aldehyde dehydrogenase, cysteine active site
InterPro IPR015590 Aldehyde dehydrogenase domain
InterPro IPR029510 Aldehyde dehydrogenase, glutamic acid active site
InterPro IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
InterPro IPR016162 Aldehyde dehydrogenase N-terminal domain
InterPro IPR016161 Aldehyde/histidinol dehydrogenase
Protein Ontology PR:000003927 fatty aldehyde dehydrogenase
References
(Earliest) J:6570 Timms GP, et al., Genetics of aldehyde dehydrogenase isozymes in the mouse: evidence for multiple loci and localization of Ahd-2 on chromosome 19. Genetics. 1981 Feb;97(2):327-36
(Latest) J:218413 Kitamura T, et al., Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification. Biochem J. 2015 Jan 1;465(1):79-87
All references(60)
Other
accession IDs
MGD-MRK-1207, MGD-MRK-1208, MGD-MRK-1214, MGD-MRK-1215, MGD-MRK-16379, MGD-MRK-16380, MGI:2144079, MGI:99597, MGI:99598

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory