About   Help   FAQ
Timm8a1
Gene Detail
Symbol

Name
ID
Timm8a1
translocase of inner mitochondrial membrane 8A1
MGI:1353433
Synonyms
Ddp1, DXHXS1274E, Fci-12, Tim8a
Feature Type
protein coding gene
Genetic Map
Chromosome X
56.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:134537256-134541865 bp, - strand
From VEGA annotation of GRCm38

  4610 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37878  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TIMM8A
Protein SuperFamily: mitochondrial import inner membrane translocase Tim8-Tim13, subunits Tim8/Tim13
Gene Tree: Timm8a1

Human
homologs
TIMM8A, translocase of inner mitochondrial membrane 8 homolog A (yeast)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 1678
neXtProt AC: NX_O60220

Human Synonyms: DDP, DDP1, DFN1, MTS, TIM8

Human Chr (Location): Xq22.1; chrX:101345656-101348969 (-)  GRCh38.p2

Disease Associations: (2) Diseases Associated with Human TIMM8A

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Interactions
Timm8a1 interacts with 178 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process protein targeting to mitochondrion
Component mitochondrial intermembrane space, mitochondrion
Function zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (25)    Tissues (16)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 25
cDNA source data(65)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(67) Genomic(1) cDNA(65) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000019308 (Evidence)
Ensembl Gene Model ENSMUSG00000048007 (Evidence)
Entrez Gene 30058 (Evidence)
UniGene 214504
DFCI TC1574833
DoTS DT.494522, DT.101723737
NIA Mouse Gene Index U011265, U039702
Consensus CDS Project CCDS41122.1
International Mouse Phenotyping Consortium Status Timm8a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019308 VEGA Gene Model | MGI Sequence Detail 4610 C57BL/6J ±  kb
transcript OTTMUST00000046139 VEGA | MGI Sequence Detail 1421 Not Applicable 
polypeptide OTTMUSP00000020835 VEGA | MGI Sequence Detail 97 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2)
Polymorphisms
SNPs within 2kb(26 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000029794 mitochondrial import inner membrane translocase subunit Tim8 A
References
(Earliest) J:39674 Oeltjen JC, et al., Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains. Genome Res. 1997 Apr;7(4):315-29
(Latest) J:179027 Engl G, et al., Alterations in expression levels of deafness dystonia protein 1 affect mitochondrial morphology. Hum Mol Genet. 2012 Jan 15;21(2):287-99
All references(34)
Other
accession IDs
MGI:1201786

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory