Timm8a1
Gene Detail

Symbol Name ID

Timm8a1 translocase of inner mitochondrial membrane 8A1 MGI:1353433

Synonyms

Ddp1, DXHXS1274E, Fci-12, Tim8a

Feature Type

protein coding gene

Genetic Map

Chromosome X

56.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

ChrX:134537256-134541865 bp, - strand From VEGA annotation of GRCm38   4610 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37878  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: mitochondrial import inner membrane translocase Tim8-Tim13, subunits Tim8/Tim13
Gene Tree: Timm8a1

Human homologs

Human Homolog		TIMM8A, translocase of inner mitochondrial membrane 8 homolog A (yeast)
NCBI Gene ID		1678
neXtProt AC		NX_O60220
Human Synonyms		DDP, DDP1, DFN1, MTS, TIM8
Human Chr (Location)		Xq22.1; chrX:100600644-100603957 (-)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human TIMM8A

Alleles and phenotypes

All alleles(3) : Targeted(1) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	protein targeting to mitochondrion
Component	mitochondrial intermembrane space, mitochondrion
Function	zinc ion binding

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (25)    Tissues (16)    Images (3)
Theiler Stages: 19, 23

Assay Type	Results
RNA in situ	25

cDNA source data(63)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(65) Genomic(1) cDNA(63) Other(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000019308 (Evidence)
Ensembl Gene Model	ENSMUSG00000048007 (Evidence)
Entrez Gene	30058 (Evidence)
UniGene	214504
DFCI	TC1574833
DoTS	DT.101723737, DT.494522
NIA Mouse Gene Index	U011265, U039702
Consensus CDS Project	CCDS41122.1
International Mouse Knockout Project Status	Timm8a1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000019308	VEGA Gene Model | MGI Sequence Detail	4610	C57BL/6J
transcript	OTTMUST00000046139	VEGA | MGI Sequence Detail	1421	Not Applicable
polypeptide	OTTMUSP00000020835	VEGA | MGI Sequence Detail	97	Not Applicable

All sequences(26) RefSeq(2)

Polymorphisms

SNPs(6 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000029794	mitochondrial import inner membrane translocase subunit Tim8 A

References

(Earliest) J:39674 Oeltjen JC, et al., Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains. Genome Res. 1997 Apr;7(4):315-29
(Latest) J:179027 Engl G, et al., Alterations in expression levels of deafness dystonia protein 1 affect mitochondrial morphology. Hum Mol Genet. 2012 Jan 15;21(2):287-99
All references(35)

Other accession IDs

MGI:1201786