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Rnf17
Gene Detail
 Symbol
Name
ID
Rnf17
ring finger protein 17
MGI:1353419
Synonyms MMIP-2
Feature Type protein coding gene
Genetic Map
Chromosome 14
28.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:56402697-56525032 bp, + strand
From NCBI annotation of GRCm38

  122336 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23727  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Rnf17

Human
homologs
Human Homolog RNF17, ring finger protein 17
NCBI Gene ID 56163
neXtProt AC  NX_Q9BXT8
Human Synonyms  Mmip-2, SPATA23, TDRD4
Human Chr (Location)  13q12.12; chr13:24764152-24888284 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(7) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display male infertility, azoospermia, arrest of spermatogenesis, and small testis.
 
Interactions
Rnf17 interacts with 114 markers (Mir1a-1, Mir1a-2, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell differentiation, multicellular organismal development, ...
Component cytoplasm, nucleus
Function metal ion binding, protein homodimerization activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (69)    Tissues (48)    Images (7)
Theiler Stages: 16, 18, 21, 23, 28
Assay TypeResults
RNA in situ 69
cDNA source data(28)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(29) cDNA(28) Primer pair(1)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000000365 (Evidence)
Entrez Gene30054 (Evidence)
UniGene287783
DFCITC1583584, TC1594856, TC1595486, TC1606382, TC1625580
DoTSDT.110762622, DT.110762631, DT.40179888, DT.55214177, DT.60101415
NIA Mouse Gene IndexU015678
Consensus CDS ProjectCCDS27149.1
International Mouse Knockout Project StatusRnf17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 30054 NCBI Gene Model | MGI Sequence Detail 122336 C57BL/6J ±  kb
transcript NM_001033043 RefSeq | MGI Sequence Detail 5148 Not Specified 
polypeptide Q99MV7 UniProt | EBI | MGI Sequence Detail 1640 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(16) UniProt(1)
Polymorphisms SNPs within 2kb(442 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016071 Staphylococcal nuclease (SNase-like), OB-fold
InterPro IPR002999 Tudor domain
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
Protein Ontology PR:000014103 RING finger protein 17
Graphical View of Protein Domain Structure
References (Earliest) J:46395 Gupta K, et al., Mmip1: a novel leucine zipper protein that reverses the suppressive effects of Mad family members on c-myc. Oncogene. 1998 Mar 5;16(9):1149-59
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory