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Hdgfl3 Gene Detail
Summary
  • Symbol
    Hdgfl3
  • Name
    HDGF like 3
  • Synonyms
    2700022B06Rik, Hdgfrp3, HRP-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1352760
    NCBI Gene: 29877
  • Gene Overview
    MyGene.info: HDGFL3
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:81881256-81934459 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 45.71 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    330 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1352760
protein coding gene Chr7:81881251-81934473 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032440
protein coding gene Chr7:83974694-84030470 (-)
A/J MGP_AJ_G0032418
protein coding gene Chr7:81976988-82031290 (-)
AKR/J MGP_AKRJ_G0032354
protein coding gene Chr7:83804860-83857812 (-)
BALB/cJ MGP_BALBcJ_G0032430
protein coding gene Chr7:81642880-81695552 (-)
C3H/HeJ MGP_C3HHeJ_G0032144
protein coding gene Chr7:84411607-84465147 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032921
protein coding gene Chr7:87248681-87302319 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029931
protein coding gene Chr7:84443508-84494444 (-)
CAST/EiJ MGP_CASTEiJ_G0031471
protein coding gene Chr7:75352264-75410273 (-)
CBA/J MGP_CBAJ_G0032109
protein coding gene Chr7:90166675-90226279 (-)
DBA/2J MGP_DBA2J_G0032264
protein coding gene Chr7:80506430-80559411 (-)
FVB/NJ MGP_FVBNJ_G0032218
protein coding gene Chr7:80443701-80495284 (-)
LP/J MGP_LPJ_G0032345
protein coding gene Chr7:85198497-85254115 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032255
protein coding gene Chr7:90220715-90276157 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032941
protein coding gene Chr7:83215507-83269985 (-)
PWK/PhJ MGP_PWKPhJ_G0031191
protein coding gene Chr7:73726370-73780461 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031033
protein coding gene Chr7:70211900-70267449 (-)
WSB/EiJ MGP_WSBEiJ_G0031588
protein coding gene Chr7:83578923-83633610 (-)



Homology
more
  • Human Ortholog
    HDGFL3, HDGF like 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    HDGFL3, HDGF like 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-142, HDGF2, HDGF-2, HDGFRP3, HRP-3
  • Links
    NCBI Gene ID: 50810
    neXtProt AC: NX_Q9Y3E1
    UniProt: Q9Y3E1

  • Chr Location
    15q25.2; chr15:83112738-83208018 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 32196
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: HDGFL3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Hdgfl3
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 29877 NCBI Gene Model | MGI Sequence Detail 53204 C57BL/6J ±  kb
transcript NM_013886 RefSeq | MGI Sequence Detail 5868 C57BL/6  
polypeptide Q9JMG7 UniProt | EBI | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 8
Other
Accession IDs
less
MGI:1919839
References
more
  • Summaries
    All 38
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:152865 Georgas K, et al., Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15;332(2):273-86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory