About   Help   FAQ
Cspg5
Gene Detail
Symbol

Name
ID
Cspg5
chondroitin sulfate proteoglycan 5
MGI:1352747
Synonyms
CALEB, neuroglycan C, NGC
Feature Type
protein coding gene
Genetic Map
Chromosome 9
59.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:110243783-110262575 bp, + strand
From Ensembl annotation of GRCm38

  18793 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4795  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: CSPG5
Gene Tree: Cspg5

Human
homologs
CSPG5, chondroitin sulfate proteoglycan 5 (neuroglycan C)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10675
neXtProt AC: NX_O95196

Human Synonyms: NGC

Human Chr (Location): 3p21.3; chr3:47562238-47580240 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(19) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous null mice display decreased spontaneous postsynaptic currents, increased paired-pulse ratios, and reduced long term depression during early postnatal developmental stages.
 
Interactions
Cspg5 interacts with 65 markers (Mir7-1, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process activation of mitophagy in response to mitochondrial depolarization, cell differentiation, ...
Component endoplasmic reticulum, Golgi apparatus, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (42)    Tissues (29)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 42
cDNA source data(22)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(25) cDNA(25)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000032482 (Evidence)
Entrez Gene 29873 (Evidence)
UniGene 38496
DFCI TC1579704, TC1592470, TC1595503
DoTS DT.101200289, DT.526208, DT.91354184, DT.94221346, DT.99863527
NIA Mouse Gene Index U011062
Consensus CDS Project CCDS52936.1
International Mouse Phenotyping Consortium Status Cspg5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032482 Ensembl Gene Model | MGI Sequence Detail 18793 C57BL/6J ±  kb
transcript ENSMUST00000035058 Ensembl | MGI Sequence Detail 3870 Not Applicable 
polypeptide ENSMUSP00000035058 Ensembl | MGI Sequence Detail 566 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(78 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010555 Chondroitin sulphate attachment
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR009505 Neural chondroitin sulphate proteoglycan cytoplasmic
Protein Ontology PR:000005954 chondroitin sulfate proteoglycan 5
References
(Earliest) J:59346 Aono S, et al., Genomic organization and expression pattern of mouse neuroglycan C in the cerebellar development. J Biol Chem. 2000 Jan 7;275(1):337-42
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(34)
Other
accession IDs
MGI:2143104

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory