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Stau2 Gene Detail
Summary
  • Symbol
    Stau2
  • Name
    staufen (RNA binding protein) homolog 2 (Drosophila)
  • Feature Type
    protein coding gene
  • IDs
    MGI:1352508
    NCBI Gene: 29819
  • Gene Overview
    MyGene.info: STAU2
Location & Maps
more
  • Sequence Map
    Chr1:16228674-16520112 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      291439 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 5.05 cM, cytoband A3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    STAU2, staufen double-stranded RNA binding protein 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STAU2, staufen double-stranded RNA binding protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    39K2, 39K3
  • Links
    NCBI Gene ID: 27067
    neXtProt AC: NX_Q9NUL3

  • Chr Location
    8q21.11; chr8:73420369-73747708 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8666
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: STAU2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Gene trapped
    1
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033135 VEGA Gene Model | MGI Sequence Detail 291439 C57BL/6J ±  kb
transcript OTTMUST00000086841 VEGA | MGI Sequence Detail 2907 Not Applicable  
polypeptide OTTMUSP00000047064 VEGA | MGI Sequence Detail 570 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    880 from dbSNP Build 142
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000015727 double-stranded RNA-binding protein Staufen homolog 2
  • PDB
  • InterPro Domains
    IPR014720 Double-stranded RNA-binding domain
    IPR032478 Staufen, C-terminal
Molecular
Reagents
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  • All nucleic 60
    cDNA 58
    Primer pair 2

    Microarray probesets 7
References
more
  • Summaries
    All 37
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:58925 Buchner G, et al., Identification of a novel homolog of the Drosophila staufen protein in the chromosome 8q13-q21.1 region. Genomics. 1999 Nov 15;62(1):113-8
  • Latest
    J:192772 Kusek G, et al., Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression. Cell Stem Cell. 2012 Oct 5;11(4):505-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory