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Limd1 Gene Detail
Summary
  • Symbol
    Limd1
  • Name
    LIM domains containing 1
  • Synonyms
    D9Ertd192e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1352502
    NCBI Gene: 29806
  • Gene Overview
    MyGene.info: LIMD1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:123478706-123521552 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 74.00 cM, cytoband F
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    429 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1352502
protein coding gene Chr9:123478661-123521552 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035477
protein coding gene Chr9:126528576-126576280 (+)
A/J MGP_AJ_G0035458
protein coding gene Chr9:121686104-121728944 (+)
AKR/J MGP_AKRJ_G0035391
protein coding gene Chr9:124942921-124987677 (+)
BALB/cJ MGP_BALBcJ_G0035454
protein coding gene Chr9:121619286-121663432 (+)
C3H/HeJ MGP_C3HHeJ_G0035161
protein coding gene Chr9:125393111-125436862 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035977
protein coding gene Chr9:130025352-130073365 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032859
protein coding gene Chr9:118809791-118850404 (+)
CAST/EiJ MGP_CASTEiJ_G0034466
protein coding gene Chr9:125432816-125476829 (+)
CBA/J MGP_CBAJ_G0035129
protein coding gene Chr9:134759900-134808385 (+)
DBA/2J MGP_DBA2J_G0035288
protein coding gene Chr9:121131278-121174573 (+)
FVB/NJ MGP_FVBNJ_G0035235
protein coding gene Chr9:120036952-120075818 (+)
LP/J MGP_LPJ_G0035367
protein coding gene Chr9:126864796-126911255 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035276
protein coding gene Chr9:135570520-135615224 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035996
protein coding gene Chr9:125406995-125456633 (+)
PWK/PhJ MGP_PWKPhJ_G0034170
protein coding gene Chr9:121581674-121626807 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034007
protein coding gene Chr9:125527066-125572928 (+)
WSB/EiJ MGP_WSBEiJ_G0034586
protein coding gene Chr9:125252437-125295164 (+)



Homology
more
  • Human Ortholog
    LIMD1, LIM domains containing 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    LIMD1, LIM domains containing 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 8994
    neXtProt AC: NX_Q9UGP4
    UniProt: Q9UGP4

  • Chr Location
    3p21.31; chr3:45594181-45681263 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal basal bone osteoclast numbers and bone density but are resistant to physiological and pathologic osteoclastogenic stimuli.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025239 Ensembl Gene Model | MGI Sequence Detail 42847 C57BL/6J ±  kb
transcript ENSMUST00000026269 Ensembl | MGI Sequence Detail 4848 Not Applicable  
polypeptide ENSMUSP00000026269 Ensembl | MGI Sequence Detail 668 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 196
    Genomic 1
    cDNA 192
    Primer pair 2
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1098702, MGI:2143352
References
more
  • Summaries
    All 48
    Developmental Gene Expression 10
    Gene Ontology 10
    Phenotypes 4
  • Earliest
    J:59385 Kiss H, et al., A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3. Hum Genet. 1999 Dec;105(6):552-9
  • Latest
    J:208431 Iwata J, et al., TGFbeta regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate. Development. 2014 Feb;141(4):909-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory