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Limd1
Gene Detail
Symbol

Name
ID
Limd1
LIM domains containing 1
MGI:1352502
Synonyms
D9Ertd192e
Feature Type
protein coding gene
Genetic Map
Chromosome 9
74.00 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr9:123478701-123521548 bp, + strand
From Ensembl annotation of GRCm38

  42848 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8478  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Limd1

Human
homologs
Human Homolog LIMD1, LIM domains containing 1
NCBI Gene ID 8994
neXtProt AC  NX_Q9UGP4
Human Chr (Location)  3p21.3; chr3:45594831-45681263 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(6) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit normal basal bone osteoclast numbers and bone density but are resistant to physiological and pathologic osteoclastogenic stimuli.
 
Interactions
Limd1 interacts with 253 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process cell migration, cytoplasmic mRNA processing body assembly, ...
Component adherens junction, cell junction, ...
Function metal ion binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (60)    Tissues (60)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 52
RT-PCR 8
cDNA source data(191)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(195) Genomic(1) cDNA(191) Primer pair(2) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000025239 (Evidence)
Entrez Gene29806 (Evidence)
UniGene10987
DFCITC1617933, TC1571949
DoTSDT.101340160, DT.97410363, DT.91442473, DT.537445
NIA Mouse Gene IndexU011195
Consensus CDS ProjectCCDS23660.1
International Mouse Knockout Project StatusLimd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025239 Ensembl Gene Model | MGI Sequence Detail 42848 C57BL/6J ±  kb
transcript ENSMUST00000026269 Ensembl | MGI Sequence Detail 4849 Not Applicable 
polypeptide ENSMUSP00000026269 Ensembl | MGI Sequence Detail 668 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(430 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000029595 LIM domain-containing protein 1
References
(Earliest) J:59385 Kiss H, et al., A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3. Hum Genet. 1999 Dec;105(6):552-9
(Latest) J:208431 Iwata J, et al., TGFbeta regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate. Development. 2014 Feb;141(4):909-17
All references(49)
Other
accession IDs
MGI:1098702, MGI:2143352

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory