Ndrg3
Gene Detail

Symbol

Name
ID

Ndrg3
N-myc downstream regulated gene 3
MGI:1352499

Synonyms

4833415O14Rik, Ndr3

Feature Type

protein coding gene

Genetic Map

Chromosome 2
77.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:156927345-156992056 bp, - strand From VEGA annotation of GRCm38   64712 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:40903  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 2 zebrafish

Gene Tree: Ndrg3

Human
homologs

Human Homolog		NDRG3, NDRG family member 3
NCBI Gene ID		57446
neXtProt AC		NX_Q9UGV2
Human Chr (Location)		20q11.21-q11.23; chr20:36651766-36746138 (-)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(59) : Gene trapped(57) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 

Homozygous mutation of this gene results in lethality before weaning.

 

Interactions

Ndrg3 interacts with 321 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (5 annotations)

Process	biological_process
Component	cytoplasm, extracellular vesicular exosome
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (3 records)

Data Summary: Results (102)    Tissues (58)    Images (12)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	102

cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas

Molecular
reagents

All nucleic(13) cDNA(13)
Microarray probesets(6)

Other database
links

VEGA Gene Model	OTTMUSG00000016170 (Evidence)
Ensembl Gene Model	ENSMUSG00000027634 (Evidence)
Entrez Gene	29812 (Evidence)
DFCI	TC1571931, TC1591487, TC1609078
DoTS	DT.494338, DT.55272266, DT.55173662, DT.91444512, DT.97371919, DT.94194620, DT.94194596
NIA Mouse Gene Index	U023566
Consensus CDS Project	CCDS16971.1, CCDS50780.1
International Mouse Knockout Project Status	Ndrg3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016170	VEGA Gene Model | MGI Sequence Detail	64712	C57BL/6J
transcript	OTTMUST00000038690	VEGA | MGI Sequence Detail	2612	Not Applicable
polypeptide	OTTMUSP00000017304	VEGA | MGI Sequence Detail	388	Not Applicable

All sequences(84) RefSeq(14) UniProt(4)

Polymorphisms

SNPs within 2kb(722 from dbSNP Build 137)    SNPs within 2kb including multiple locations(750)

Protein-related
information

Resource	ID	Description
InterPro	IPR004142	Ndr
Protein Ontology	PR:000011061	protein NDRG3

References

(Earliest) J:58924 Okuda T, et al., Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc. Biochem Biophys Res Commun. 1999 Dec 9;266(1):208-15
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(40)

Other
accession IDs

MGI:2139046, MGI:2442824