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Ndrg3
Gene Detail
Symbol

Name
ID
Ndrg3
N-myc downstream regulated gene 3
MGI:1352499
Synonyms
4833415O14Rik, Ndr3
Feature Type
protein coding gene
Genetic Map
Chromosome 2
77.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:156927345-156992056 bp, - strand
From VEGA annotation of GRCm38

  64712 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40903  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 2 zebrafish

Gene Tree: Ndrg3

Human
homologs
Human Homolog NDRG3, NDRG family member 3
NCBI Gene ID 57446
neXtProt AC  NX_Q9UGV2
Human Chr (Location)  20q11.21-q11.23; chr20:36651766-36746138 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(59) : Gene trapped(57) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in lethality before weaning.
 
Interactions
Ndrg3 interacts with 321 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process biological_process
Component cytoplasm, extracellular vesicular exosome
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (102)    Tissues (58)    Images (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 102
cDNA source data(12)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000016170 (Evidence)
Ensembl Gene ModelENSMUSG00000027634 (Evidence)
Entrez Gene29812 (Evidence)
DFCITC1571931, TC1591487, TC1609078
DoTSDT.494338, DT.55173662, DT.55272266, DT.91444512, DT.94194596, DT.94194620, DT.97371919
NIA Mouse Gene IndexU023566
Consensus CDS ProjectCCDS16971.1, CCDS50780.1
International Mouse Knockout Project StatusNdrg3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016170 VEGA Gene Model | MGI Sequence Detail 64712 C57BL/6J ±  kb
transcript OTTMUST00000038690 VEGA | MGI Sequence Detail 2612 Not Applicable 
polypeptide OTTMUSP00000017304 VEGA | MGI Sequence Detail 388 Not Applicable 

For the selected sequences
All sequences(89) RefSeq(16) UniProt(7)
Polymorphisms
SNPs within 2kb(722 from dbSNP Build 137)    SNPs within 2kb including multiple locations(750)
Protein-related
information
ResourceIDDescription
InterPro IPR004142 Ndr
Protein Ontology PR:000011061 protein NDRG3
References
(Earliest) J:58924 Okuda T, et al., Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc. Biochem Biophys Res Commun. 1999 Dec 9;266(1):208-15
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGI:2139046, MGI:2442824

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory