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Ndrg2
Gene Detail
 Symbol
Name
ID
Ndrg2
N-myc downstream regulated gene 2
MGI:1352498
Synonyms Ndr2
Feature Type protein coding gene
Genetic Map
Chromosome 14
26.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:51905271-51913488 bp, - strand
From NCBI annotation of GRCm38

  8218 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22785  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Ndrg2

Human
homologs
Human Homolog NDRG2, NDRG family member 2
NCBI Gene ID 57447
neXtProt AC  NX_Q9UN36
Human Synonyms  SYLD
Human Chr (Location)  14q11.2; chr14:21016763-21070872 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit numerous vertebral transformation.
 
Interactions
Ndrg2 interacts with 158 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cell differentiation, multicellular organismal development, ...
Component cell projection, centrosome, ...
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (459)    Tissues (230)    Images (50)
Theiler Stages: 14, 16, 21, 22, 23, 27, 28
Assay TypeResults
RNA in situ 454
RT-PCR 5
cDNA source data(220)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(223) cDNA(220) Primer pair(3)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000004558 (Evidence)
Entrez Gene29811 (Evidence)
UniGene26722
DFCITC1573601, TC1700921
DoTSDT.101206833, DT.87073021, DT.94372322
NIA Mouse Gene IndexU035528
PDB2QMQ
Consensus CDS ProjectCCDS27047.1, CCDS49486.1
International Mouse Knockout Project StatusNdrg2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 29811 NCBI Gene Model | MGI Sequence Detail 8218 C57BL/6J ±  kb
transcript NM_013864 RefSeq | MGI Sequence Detail 2157 C57BL/6 
polypeptide Q9QYG0 UniProt | EBI | MGI Sequence Detail 371 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(36) UniProt(2)
Polymorphisms SNPs within 2kb(104 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004142 Ndr
Protein Ontology PR:000011060 protein NDRG2
Graphical View of Protein Domain Structure
References (Earliest) J:58924 Okuda T, et al., Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc. Biochem Biophys Res Commun. 1999 Dec 9;266(1):208-15
(Latest) J:195311 Chiba S, et al., NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15. EMBO J. 2013 Mar 20;32(6):874-85
All references(51)
Other
accession IDs
MGI:2145602, MGI:2145752

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory