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Ndrg2
Gene Detail
Symbol

Name
ID
Ndrg2
N-myc downstream regulated gene 2
MGI:1352498
Synonyms
Ndr2
Feature Type
protein coding gene
Genetic Map
Chromosome 14
26.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:51905271-51913488 bp, - strand
From Ensembl annotation of GRCm38

  8218 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22785  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Ndrg2

Human
homologs
Human Homolog NDRG2, NDRG family member 2
NCBI Gene ID 57447
neXtProt AC  NX_Q9UN36
Human Synonyms  SYLD
Human Chr (Location)  14q11.2; chr14:21016763-21070872 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit numerous vertebral transformation.
 
Interactions
Ndrg2 interacts with 158 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cell differentiation, multicellular organismal development, ...
Component cell projection, centrosome, ...
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (459)    Tissues (230)    Images (50)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 454
RT-PCR 5
cDNA source data(220)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(223) cDNA(220) Primer pair(3)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000004558 (Evidence)
Entrez Gene29811 (Evidence)
UniGene26722
DFCITC1573601, TC1700921
DoTSDT.87073021, DT.101206833, DT.94372322
NIA Mouse Gene IndexU035528
PDB2QMQ
Consensus CDS ProjectCCDS27047.1, CCDS49486.1
International Mouse Knockout Project StatusNdrg2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004558 Ensembl Gene Model | MGI Sequence Detail 8218 C57BL/6J ±  kb
transcript ENSMUST00000004673 Ensembl | MGI Sequence Detail 2157 Not Applicable 
polypeptide ENSMUSP00000004673 Ensembl | MGI Sequence Detail 371 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(36) UniProt(3)
Polymorphisms
SNPs within 2kb(104 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004142 Ndr
Protein Ontology PR:000011060 protein NDRG2
References
(Earliest) J:58924 Okuda T, et al., Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc. Biochem Biophys Res Commun. 1999 Dec 9;266(1):208-15
(Latest) J:195311 Chiba S, et al., NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15. EMBO J. 2013 Mar 20;32(6):874-85
All references(51)
Other
accession IDs
MGI:2145602, MGI:2145752

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory