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Zfp385a
Gene Detail
Symbol

Name
ID
Zfp385a
zinc finger protein 385A
MGI:1352495
Synonyms
Hzf, Zfp385
Feature Type
protein coding gene
Genetic Map
Chromosome 15
58.88 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:103313895-103340086 bp, - strand
From NCBI annotation of GRCm38

  26192 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8479  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ZNF385A
Gene Tree: Zfp385a

Human
homologs
ZNF385A, zinc finger protein 385A
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 25946
neXtProt AC: NX_Q96PM9

Human Synonyms: HZF, RZF, ZFP385, ZNF385

Human Chr (Location): 12q13.13; chr12:54369129-54391305 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(16) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display partial postnatal lethality with gastrointestinal and intracranial hemorrhages, abnormal megakaryocyte development, and reduced body size.
 
Interactions
Zfp385a interacts with 272 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process apoptotic process, cell cycle, ...
Component cell projection, cytoplasm, ...
Function metal ion binding, mRNA 3'-UTR binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (194)    Tissues (116)    Images (52)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 122
In situ reporter (knock in) 14
Northern blot 8
RT-PCR 50
cDNA source data(53)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(59) cDNA(54) Primer pair(4) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000000552 (Evidence)
Entrez Gene 29813 (Evidence)
UniGene 14099
DFCI TC1580418
DoTS DT.527937, DT.101366409
NIA Mouse Gene Index U036712
Consensus CDS Project CCDS49743.1
International Mouse Phenotyping Consortium Status Zfp385a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 29813 NCBI Gene Model | MGI Sequence Detail 26192 C57BL/6J ±  kb
transcript NM_013866 RefSeq | MGI Sequence Detail 2320 C57BL/6 
polypeptide Q8VD12 UniProt | EBI | MGI Sequence Detail 386 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(14) UniProt(1)
Polymorphisms
SNPs within 2kb(73 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR003604 Zinc finger, U1-type
Protein Ontology PR:000017859 zinc finger protein 385A
Graphical View of Protein Domain Structure
References
(Earliest) J:58923 Hidaka M, et al., Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells. Mech Dev. 2000 Jan;90(1):3-15
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory