nuclear receptor subfamily 2, group F, member 6
Mice homozygous for a knock-out allele exhibit partial agenesis of the locus coeruleus, increased thermal nociception, and defective circadian behavior including a delayed entrainment to shifted light-dark cycles and reduced anticipatory locomotor activity in restricted feeding experiments.
|Process||detection of temperature stimulus involved in sensory perception of pain, entrainment of circadian clock by photoperiod, ...|
|Function||DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, ...|
|InterPro||IPR008946||Nuclear hormone receptor, ligand-binding|
|InterPro||IPR000536||Nuclear hormone receptor, ligand-binding, core|
|InterPro||IPR001723||Steroid hormone receptor|
|InterPro||IPR003068||Transcription factor COUP|
|InterPro||IPR013088||Zinc finger, NHR/GATA-type|
|InterPro||IPR001628||Zinc finger, nuclear hormone receptor-type|
|Protein Ontology||PR:000029648||nuclear receptor subfamily 2 group F member 6|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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