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Pdxk Gene Detail
Summary
  • Symbol
    Pdxk
  • Name
    pyridoxal (pyridoxine, vitamin B6) kinase
  • Synonyms
    2310036D04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351869
    NCBI Gene: 216134
  • Gene Overview
    MyGene.info: PDXK
Location & Maps
more
  • Sequence Map
    Chr10:78436744-78464975 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      28232 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PDXK, pyridoxal kinase
  • Vertebrate Orthologs
    12
  • Human Ortholog
    PDXK, pyridoxal kinase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C21orf124, C21orf97, HEL-S-1a, PKH, PNK, PRED79
  • Links
    NCBI Gene ID: 8566
    neXtProt AC: NX_O00764
    UniProt: O00764

  • Chr Location
    21q22.3; chr21:43719097-43762307 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 2731
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;3 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PDXK
  • Gene Tree
    Pdxk
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    28
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    388
  • Tissues
    185
  • cDNA Data
    16
  • Literature Summary
    5
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020292 VEGA Gene Model | MGI Sequence Detail 28232 C57BL/6J ±  kb
transcript OTTMUST00000048157 VEGA | MGI Sequence Detail 5124 Not Applicable  
polypeptide OTTMUSP00000021998 VEGA | MGI Sequence Detail 312 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    109 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    Genomic 11
    cDNA 17
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1916848, MGI:2143917, MGI:3034915
References
more
  • Summaries
    All 52
    Developmental Gene Expression 5
    Diseases 2
    Gene Ontology 4
    Phenotypes 21
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:238763 Choo HJ, et al., Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import. Stem Cells. 2016 Jul 19;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/20/2017
MGI 6.10 		The Jackson Laboratory