About   Help   FAQ
Slco1a5
Gene Detail
Symbol

Name
ID
Slco1a5
solute carrier organic anion transporter family, member 1a5
MGI:1351865
Synonyms
Oatp3, Slc21a7
Feature Type
protein coding gene
Genetic Map
Chromosome 6
73.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:142234227-142322981 bp, - strand
From VEGA annotation of GRCm38

  88755 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56603  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Slco1a5

Human
homologs
Human Homolog SLCO1A2, solute carrier organic anion transporter family, member 1A2
NCBI Gene ID 6579
neXtProt AC  NX_P46721
Human Synonyms  OATP, OATP1A2, OATP-A, SLC21A3
Human Chr (Location)  12p12; chr12:21264600-21395437 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Genomic Mutations involving Slco1a5 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in decreased percentage of CD8 ells and increased percentage of B cells in the peripheral blood.
 
Interactions
Slco1a5 interacts with 282 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Expression
Literature Summary: (2 records)
Data Summary: Results (150)    Tissues (100)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 150
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(19) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024218 (Evidence)
Ensembl Gene ModelENSMUSG00000063975 (Evidence)
Entrez Gene108096 (Evidence)
UniGene206599
DFCITC1583452, TC1589057, TC1664309
DoTSDT.521906, DT.91322365, DT.99854148
NIA Mouse Gene IndexU028002
Consensus CDS ProjectCCDS57464.1
International Mouse Knockout Project StatusSlco1a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024218 VEGA Gene Model | MGI Sequence Detail 88755 C57BL/6J ±  kb
transcript OTTMUST00000059262 VEGA | MGI Sequence Detail 2586 Not Applicable 
polypeptide OTTMUSP00000062819 VEGA | MGI Sequence Detail 670 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(8) UniProt(4)
Polymorphisms
SNPs within 2kb(972 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002350 Kazal domain
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
InterPro IPR004156 Organic anion transporter polypeptide OATP
Protein Ontology PR:000015967 solute carrier organic anion transporter family member 1A5
References
(Earliest) J:66643 Walters HC, et al., Expression, transport properties, and chromosomal location of organic anion transporter subtype 3. Am J Physiol Gastrointest Liver Physiol. 2000 Dec;279(6):G1188-200
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory