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Slco1a5
Gene Detail
 Symbol
Name
ID
Slco1a5
solute carrier organic anion transporter family, member 1a5
MGI:1351865
Synonyms Oatp3, Slc21a7
Feature Type protein coding gene
Genetic Map
Chromosome 6
73.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:142234227-142322981 bp, - strand
From VEGA annotation of GRCm38

  88755 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56603  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Slco1a5

Human
homologs
Human Homolog SLCO1A2, solute carrier organic anion transporter family, member 1A2
NCBI Gene ID 6579
neXtProt AC  NX_P46721
Human Synonyms  OATP, OATP1A2, OATP-A, SLC21A3
Human Chr (Location)  12p12; chr12:21264600-21395437 (-)  GRCh38
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
 
Homozygous mutation of this gene results in decreased percentage of CD8 ells and increased percentage of B cells in the peripheral blood.
 
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process amino acid transmembrane transport, bile acid and bile salt transport, ...
Component brush border membrane, integral component of membrane, ...
Function bile acid transmembrane transporter activity, monocarboxylic acid transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (150)    Tissues (100)    Images (23)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 150
cDNA source data(19)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(21) cDNA(19) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000024218 (Evidence)
Ensembl Gene ModelENSMUSG00000063975 (Evidence)
Entrez Gene108096 (Evidence)
UniGene206599
DFCITC1583452, TC1589057, TC1664309
DoTSDT.521906, DT.91322365, DT.99854148
NIA Mouse Gene IndexU028002
Consensus CDS ProjectCCDS57464.1
International Mouse Knockout Project StatusSlco1a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024218 VEGA Gene Model | MGI Sequence Detail 88755 C57BL/6J ±  kb
transcript OTTMUST00000059262 VEGA | MGI Sequence Detail 2586 Not Applicable 
polypeptide OTTMUSP00000062819 VEGA | MGI Sequence Detail 670 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(8) UniProt(4)
Polymorphisms SNPs within 2kb(972 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002350 Kazal domain
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
InterPro IPR004156 Organic anion transporter polypeptide OATP
Protein Ontology PR:000015967 solute carrier organic anion transporter family member 1A5
References (Earliest) J:66643 Walters HC, et al., Expression, transport properties, and chromosomal location of organic anion transporter subtype 3. Am J Physiol Gastrointest Liver Physiol. 2000 Dec;279(6):G1188-200
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory