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Abca8b Gene Detail
Summary
  • Symbol
    Abca8b
  • Name
    ATP-binding cassette, sub-family A (ABC1), member 8b
  • Synonyms
    Abca8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351668
    NCBI Gene: 27404
  • Gene Overview
    MyGene.info: ABCA8
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:109932568-109995840 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 72.88 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351668
 protein coding gene Chr11:109932190-109995845 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019340
 protein coding gene Chr11:113520097-113590246 (-)
A/J MGP_AJ_G0019308
 protein coding gene Chr11:108623514-108687306 (-)
AKR/J MGP_AKRJ_G0019277
 protein coding gene Chr11:111876996-111945360 (-)
BALB/cJ MGP_BALBcJ_G0019282
 protein coding gene Chr11:109044215-109111769 (-)
C3H/HeJ MGP_C3HHeJ_G0019091
 protein coding gene Chr11:112165063-112232600 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019732
 protein coding gene Chr11:116948294-117023072 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017355
 protein coding gene Chr11:105819926-105881652 (-)
CAST/EiJ MGP_CASTEiJ_G0018644
 protein coding gene Chr11:113319198-113397208 (-)
CBA/J MGP_CBAJ_G0019060
 protein coding gene Chr11:121789439-121857081 (-)
DBA/2J MGP_DBA2J_G0019172
 protein coding gene Chr11:108085888-108152681 (-)
FVB/NJ MGP_FVBNJ_G0019163
 protein coding gene Chr11:107571028-107634602 (-)
LP/J MGP_LPJ_G0019242
 protein coding gene Chr11:113934065-114004982 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019194
 protein coding gene Chr11:120908704-120980264 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019769
 protein coding gene Chr11:112432969-112502940 (-)
PWK/PhJ MGP_PWKPhJ_G0018409
 protein coding gene Chr11:109255792-109322400 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018201
 protein coding gene Chr11:112250856-112314485 (-)
WSB/EiJ MGP_WSBEiJ_G0018696
 protein coding gene Chr11:112361598-112430103 (-)



Homology
more
  • Human Ortholog
    ABCA8, ATP binding cassette subfamily A member 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ABCA8, ATP binding cassette subfamily A member 8
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10351
    neXtProt AC: NX_O94911
    UniProt: O94911

  • Chr Location
    17q24.2; chr17:68867285-68955426 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    118
  • Tissues
    111
  • cDNA Data
    14
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27404 NCBI Gene Model | MGI Sequence Detail 63273 C57BL/6J ±  kb
transcript NM_013851 RefSeq | MGI Sequence Detail 7407 C57BL/6  
polypeptide Q8K440 UniProt | EBI | MGI Sequence Detail 1620 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:60841 Schriml LM, et al., Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus. Genomics. 2000 Feb 15;64(1):24-31
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/06/2018
MGI 6.13 		The Jackson Laboratory