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Ptdss2
Gene Detail
Symbol

Name
ID
Ptdss2
phosphatidylserine synthase 2
MGI:1351664
Synonyms
PSS2
Feature Type
protein coding gene
Genetic Map
Chromosome 7
86.39 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:141122382-141157021 bp, + strand
From VEGA annotation of GRCm38

  34640 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8462  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PTDSS2
Protein SuperFamily: phosphatidylserine synthase 1, eukaryotic type
Gene Tree: Ptdss2

Human
homologs
PTDSS2, phosphatidylserine synthase 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 81490
neXtProt AC: NX_Q9BVG9

Human Synonyms: PSS2

Human Chr (Location): 11p15.5; chr11:448271-491399 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(112) : Gene trapped(109) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Disruption of this gene causes infertility in about 10% of homozygous males. The remaining males and all females were fertile.
 
Interactions
Ptdss2 interacts with 184 markers (Mir18b, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (151)    Tissues (115)    Images (36)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 118
In situ reporter (knock in) 11
Northern blot 16
RT-PCR 6
cDNA source data(21)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ptdss2    NEW 
Molecular
reagents
All nucleic(22) cDNA(21) Primer pair(1)
Microarray probesets(11)
Other database
links
VEGA Gene Model OTTMUSG00000037303 (Evidence)
Ensembl Gene Model ENSMUSG00000025495 (Evidence)
Entrez Gene 27388 (Evidence)
DFCI TC1612315, TC1575462, TC1586992
DoTS DT.529890, DT.97414539
EC 2.7.8.29
Consensus CDS Project CCDS22001.1
International Mouse Phenotyping Consortium Status Ptdss2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037303 VEGA Gene Model | MGI Sequence Detail 34640 C57BL/6J ±  kb
transcript OTTMUST00000096269 VEGA | MGI Sequence Detail 3039 Not Applicable 
polypeptide OTTMUSP00000053763 VEGA | MGI Sequence Detail 473 Not Applicable 

For the selected sequences
All sequences(77) RefSeq(8) UniProt(6)
Polymorphisms
SNPs within 2kb(131 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004277 Phosphatidyl serine synthase
Protein Ontology PR:000013416 phosphatidylserine synthase 2
References
(Earliest) J:57025 Stone SJ, et al., Cloning and expression of murine liver phosphatidylserine synthase (PSS)-2: differential regulation of phospholipid metabolism by PSS1 and PSS2. Biochem J. 1999 Aug 15;342(Pt 1):57-64
(Latest) J:190989 Kimura AK, et al., Phosphatidylserine synthase 2: high efficiency for synthesizing phosphatidylserine containing docosahexaenoic acid. J Lipid Res. 2013 Jan;54(1):214-22
All references(41)
Other
accession IDs
MGI:2141985, MGI:2142082

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory