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Abcf2 Gene Detail
Summary
  • Symbol
    Abcf2
  • Name
    ATP-binding cassette, sub-family F (GCN20), member 2
  • Synonyms
    0710005O05Rik, Drr3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351657
    NCBI Gene: 27407
Location & Maps
more
  • Sequence Map
    Chr5:24565345-24577467 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12123 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ABCF2, ATP binding cassette subfamily F member 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ABCF2, ATP binding cassette subfamily F member 2
    Orthology source: HomoloGene
  • Synonyms
    ABC28, EST133090, HUSSY18, HUSSY-18
  • Links
    NCBI Gene ID: 10061
    neXtProt AC: NX_Q9UG63

  • Chr Location
    7q36; chr7:151207830-151227374 (-)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    22
  • Chemically induced (other)
    2
  • Gene trapped
    14
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Abcf2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000053669 VEGA Gene Model | MGI Sequence Detail 12123 C57BL/6J ±  kb
transcript OTTMUST00000133678 VEGA | MGI Sequence Detail 2569 Not Applicable  
polypeptide OTTMUSP00000071015 VEGA | MGI Sequence Detail 628 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    80 from dbSNP Build 137
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029256 ATP-binding cassette sub-family F member 2
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR017871 ABC transporter, conserved site
    IPR032781 ABC-transporter extension domain
    IPR003439 ABC transporter-like
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 153
    cDNA 152
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
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MGI:1298380, MGI:1924146
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:35907 Sam M, et al., A novel family of repeat sequences in the mouse genome responsive to retinoic acid. Mamm Genome. 1996 Oct;7(10):741-8
  • Latest
    J:207897 Krahling AM, et al., CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending. PLoS Genet. 2013 Dec;9(12):e1003960

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory