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Slc14a1
Gene Detail
 Symbol
Name
ID
Slc14a1
solute carrier family 14 (urea transporter), member 1
MGI:1351654
Synonyms 2610507K20Rik, 3021401A05Rik, UT-B
Feature Type protein coding gene
Genetic Map
Chromosome 18
52.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:78100091-78142119 bp, - strand
From VEGA annotation of GRCm38

  42029 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9285  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: urea transporter
Gene Tree: Slc14a1

Human
homologs
Human Homolog SLC14A1, solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
NCBI Gene ID 6563
neXtProt AC  NX_Q13336
Human Synonyms  HsT1341, HUT11, JK, RACH1, RACH2, UT1, UT-B1, UTE
Human Chr (Location)  18q11-q12; chr18:45723875-45752520 (+)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
 
Mice homozygous for disruptions in this gene display a grossly normal phenotype although they have an inability to concentrate urea in urine.
 
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process transmembrane transport, transport, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function urea channel activity, urea transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (291)    Tissues (207)    Images (42)
Theiler Stages: 21, 22, 23, 26, 27, 28
Assay TypeResults
RNA in situ 291
cDNA source data(38)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(40) cDNA(38) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000034695 (Evidence)
Ensembl Gene ModelENSMUSG00000059336 (Evidence)
Entrez Gene108052 (Evidence)
UniGene33832
DFCITC1577026, TC1689310
DoTSDT.101360211, DT.110770935, DT.91311285
NIA Mouse Gene IndexU038587
Consensus CDS ProjectCCDS29360.1, CCDS50330.1
International Mouse Knockout Project StatusSlc14a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034695 VEGA Gene Model | MGI Sequence Detail 42029 C57BL/6J ±  kb
transcript OTTMUST00000088107 VEGA | MGI Sequence Detail 2217 Not Applicable 
polypeptide OTTMUSP00000048005 VEGA | MGI Sequence Detail 440 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(6) UniProt(2)
Polymorphisms PCR(1) : SNPs within 2kb(260 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004937 Urea transporter
Protein Ontology PR:000014938 urea transporter 1
References (Earliest) J:59121 Fenton RA, et al., The murine urea transporter genes Slc14a1 and Slc14a2 occur in tandem on chromosome 18. Cytogenet Cell Genet. 1999;87(1-2):95-6
(Latest) J:201982 Raghuram N, et al., Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin. J Cell Biol. 2013 Oct 14;203(1):57-71
All references(40)
Other
accession IDs
MGI:1917932, MGI:1919392

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory