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Yme1l1 Gene Detail
Summary
  • Symbol
    Yme1l1
  • Name
    YME1-like 1 (S. cerevisiae)
  • Synonyms
    ATP-dependent metalloprotease FtsH1, Ftsh
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351651
    NCBI Gene: 27377
  • Gene Overview
    MyGene.info: YME1L1
Location & Maps
more
  • Sequence Map
    Chr2:23156369-23199260 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      42892 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 15.24 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    YME1L1, YME1 like 1 ATPase
  • Vertebrate Orthologs
    11
  • Human Ortholog
    YME1L1, YME1 like 1 ATPase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FTSH, MEG4, PAMP, YME1L
  • Links
    NCBI Gene ID: 10730
    neXtProt AC: NX_Q96TA2

  • Chr Location
    10p14; chr10:27110111-27155278 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011633 VEGA Gene Model | MGI Sequence Detail 42892 C57BL/6J ±  kb
transcript OTTMUST00000027219 VEGA | MGI Sequence Detail 4707 Not Applicable  
polypeptide OTTMUSP00000012381 VEGA | MGI Sequence Detail 715 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    87 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 139
    cDNA 139

    Microarray probesets 8
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:62529 Coppola M, et al., Identification and characterization of YME1L1, a novel paraplegin-related gene. Genomics. 2000 May 15;66(1):48-54
  • Latest
    J:229455 Wai T, et al., Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice. Science. 2015 Dec 4;350(6265):aad0116

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory